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Found 4 essays matching the above criteria.

1. 1. Evaluation of accuracy in simultaneous dual-radionuclide activity quantification in preclinical instruments – scintillation counter, digital autoradiography and micro-SPECT/CT

   University essay from Lunds universitet/Sjukhusfysikerutbildningen

   Author : Jonas Ahlstedt; [2012]
   Keywords : Medicine and Health Sciences;

   Abstract : Introduction: The development and optimization of methods for multi-radionuclide measurements in preclinical in vivo and ex vivo SPECT imaging could potentially improve studies in which more than one pharmaceutical is being investigated. The aim of this study is to quantitatively compare and evaluate different methods for these types of measurements using three different modalities – a small animal SPECT/CT, a scintillation counter and a digital autoradiography instrument. READ MORE

3. 2. A Technical Validation of The PET/SPECT/CT (Triumph) Scanner

   University essay from Enheten för biomedicinsk strålningsvetenskap

   Author : Ludvig Larsson Åkerman; [2011]
   Keywords : technical validation; triumph; pet; spect; ct; scanner;

   Abstract : Positron Emission Tomography (PET) plays a very important role in the field of drugdevelopment already in the preclinical phase. This is done by using positron labeled molecules for different approaches/methodologies such as cell analysis, frozen section autoradiography, homogenate binding, organ distribution and at the end in vivo small-animal PET imaging. READ MORE

4. 3. Local Delivery of Bisphosphonates from FibMat Matrix

   University essay from Institutionen för fysik, kemi och biologi

   Author : Henrik Aronsson; [2008]
   Keywords : FibMat; matrix; bisphosphonate; fibrinogen; thrombin; implant; coagulation assay; gamma irradiation; bone resorption; liquid scintillation; autoradiography; local delivery; drug;

   Abstract : Improving the functionality and reducing revision rates are important driving forces in the development of orthopaedic implants. FibMat is a fibrinogen based matrix developed towards commercialisation by the company Optovent AB. This matrix can be coated on implants and act as a local drug delivery system for bisphosphonates (BPs). READ MORE

5. 4. Polyhalogenated organic pollutants in amphibians

   University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

   Author : Pushkar Kulkarni; [2005]
   Keywords : 2; 2 ; 4; 4 ; 5-pentabromodiphenyl ether; BDE 99; PBDE; tissue disposition; frogs; Xenopus tropicalis; polyhalogenated organic pollutants;

   Abstract : Polyhalogenated organic pollutants are xenobiotics, which are believed to cause considerable environmental pollution and human health problems as a result of their persistence, toxicity, and transformation into hazardous metabolites. These chemicals are persistent and are biomagnificated in the ecosystem. READ MORE