Essays about: "cytotoxic"

Showing result 1 - 5 of 52 essays containing the word cytotoxic.

  1. 1. Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs

    University essay from Uppsala universitet/Theranostics

    Author : Astrid Haraldsson; [2023]
    Keywords : PNA; pretargeting; cancer therapy; cytotoxic payload;

    Abstract : One of the major challenges in cancer treatment is delivering high enough doses of active substance specifically to cancer cells without accumulation in healthy organs. Pretargeting has emerged as a potential solution, where the delivery of a cancer recognizing (primary) agent and a cancer killing (secondary) agent are separated. READ MORE

  3. 2. Investigating the crosstalk between estrogen receptor beta in colorectal cancer and tumor-associated macrophages

    University essay from KTH/Proteinvetenskap

    Author : Alicia Bodin; [2023]
    Keywords : estrogen; macrophages; colorectal cancer; qPCR; cell culture; östrogen; makrofager; tjocktarmscancer; qPCR; cellodling;

    Abstract : Tjock-och ändtarmscancer (kolorektalcancer) är den tredje vanligaste cancertypen och den näst vanligaste cancer-relaterade dödsorsaken i världen. Östrogen har visat sig ha en skyddande roll mot kolorektalcancer och östrogenreceptor beta är den dominerande östrogenreceptorn i normalt kolonepitel. READ MORE

  4. 3. Development of a cell killing adenovirus with a novel cytotoxic transgene

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Author : Carl Blomqvist; [2023]
    Keywords : ;

    Abstract : Cancer is among the most common causes of human deaths globally. Because of limitations and adverse effects of conventional cancer treatments, the need for new treatments is imminent. READ MORE

  5. 4. A Single-Nucleus RNA Sequencing Analysis of HERVs and LINE1s in Alzheimer's and Parkinson's Disease

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Stein Acker; [2022]
    Keywords : Biology and Life Sciences;

    Abstract : Transposable elements (TEs) are mobile genetic elements that make up roughly 50% of the human genome, with retrotransposons (or transposons which retrotranspose via an RNA intermediate) making up the vast majority of these elements. Recent studies have suggested that TEs could play a role in many neurological conditions, including ALS and dementia. READ MORE

  6. 5. Functionalization of nanofibrillated cellulose with the host defense peptide KR-12

    University essay from Uppsala universitet/Nanoteknologi och funktionella material

    Author : Alina Pavelescu; [2021]
    Keywords : KR-12; cellulose;

    Abstract : When the process of wound healing is disturbed, chronic wounds may develop. Chronic wounds heal very slowly over long periods of time, and require specialised care in order to prevent further infection. This causes considerable suffering to the patient and increased healthcare costs. READ MORE