Essays about: "genome editing"

Showing result 1 - 5 of 18 essays containing the words genome editing.

  1. 1. Establishing novel approaches for assessing safety of genome-editing-based therapeutics

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Noorul Shaheen Sheikh Farid; [2023]
    Keywords : ;

    Abstract : Genome editing based medicines are a new therapeutic modality being developed. They show great promise for a spectrum of genetic diseases lacking conventional treatment strategies. A major obstacle that prevents such therapies to reach the clinic is their safety. READ MORE

  3. 2. Compounds screening for the identification of novel drug to improve the Knock in efficiency mediated by CRISPR-Cas9

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Evangelia Anagnostou; [2023]
    Keywords : Genome editing; Knock in; HDR; CRISPR-Cas9; screening; NHEJ;

    Abstract : Genome editing is an exciting field that allows for the precise modification of an organism's DNA. One of the most advanced tools in this area is CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9), which creates a DSB (Double-strand break) at a specific location in the genome. READ MORE

  4. 3. mRNA-based pharmaceuticals : A literature study based on current knowledge of mRNA

    University essay from Uppsala universitet/Institutionen för kemi - Ångström

    Author : Alicia Andersson; Isabella Åkerfeldt; Amanda Borgenstam; Ellinor Olsson; Adam Nyström; [2022]
    Keywords : mRNA-pharmaceuticals; mRNA therapies; mRNA vaccines; mRNA components; mRNA design; and mRNA applications.;

    Abstract : This literature study provides a comprehensive overview of the current knowledge of mRNA-based pharmaceuticals, technologies and applications.  mRNA-based pharmaceuticals have newly been bought into focus as a potential brand-new drug class and many believe that it has the potential to transform areas of medicine. READ MORE

  5. 4. Exploration of the hereditary cause of sex ratio distortion in horses

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Susan Ott; [2021]
    Keywords : Sex ratio; horse; selfish genetic elements; meiotic drive; Icelandic horse; Standardbred horse; Coldblooded trotters; heritability; Trivers-Willard hypothesis; pedigree data;

    Abstract : Even sex ratios are seen as evolutionarily stable and are maintained by a selection against a skewed sex ratio. However, sometimes sex ratios at birth are skewed towards one sex. Reasons for this phenomenon are often unknown. READ MORE

  6. 5. CRISPR AND THETREATMENT/EN DISTINCTION : On Vagueness, Borderline Cases and Germline Genome Editing

    University essay from Umeå universitet/Institutionen för idé- och samhällsstudier

    Author : Ellen Svensson; [2021]
    Keywords : CRISPR; Treatment; Enhancement; Vagueness; Borderline cases; Slippery slope; Germline genome editing; GGE; Gene editing; Distinction; Ethics; Radical Enhancement; Human Nature; Eugenics;

    Abstract : In this thesis, I argue that the treatment/enhancement distinction that is central to the ethical debate concerning germline genome editing and CRISPR is too vague to be ethically and normatively guiding. The problem of vagueness is twofold, being both a semantic and epistemic issue. READ MORE