Essays about: "genome editing"

Showing result 11 - 15 of 18 essays containing the words genome editing.

  1. 11. Preimplantation genetic diagnosis and therapy in humans- Opportunities and risks

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Rickard Hedberg; [2020]
    Keywords : Preimplantation genetic diagnosis; CRISPR-Cas systems; gene editing; germline; genome; ethics; autonomy; beneficence; risks.;

    Abstract : IntroductionPreimplantation Genetic Diagnosis (PGD) was developed in the 1990s and has been used since to diagnose and discard embryos with genetic conditions or chromosomal abnormalities. CRISPR-Cas9 was discovered in 2012 and has been used in research, but has not become clinical practice on humans yet. READ MORE

  3. 12. The impact of CRISPR/Cas9 generated mutations in pioneer transcription factors FOXA1 and GATA3 on oestrogen receptor function

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Miroslav Bobrik; [2018]
    Keywords : Biology and Life Sciences;

    Abstract : Breast cancer is the most common cancer among women and two thirds of all breast cancers are classified as oestrogen receptor positive. ER is a transcription factor that regulates gene expression and promote cell proliferation that is critical in mammary gland development, and its aberrant activity is commonly present in breast cancer. READ MORE

  4. 13. Biofortification of Cassava

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Linnea Almqvist; [2018]
    Keywords : Biofortification; GMO; CRISPR Cas9; Vitamin A; Cassava; CRISPR; Gene editing; Beta carotene; Genetic engineering; Applied biochemistry; Agriculture and Food Sciences;

    Abstract : Cassava, Manihot esculenta, is the third most important staple crop in tropical re- gions. Cassava is a fibrous root that is tolerant to drought and has a flexible harvest period making it a reliable crop under poorer farming conditions (FAO, 2008). READ MORE

  5. 14. Green and red fluorescent protein tagging of endogenous proteins in glioblastoma using the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 system

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Jenny Lindvall; [2016]
    Keywords : Glioblastoma; Cancer stem cells; CRISPR Cas9; Nestin; GFAP; GFP; RFP;

    Abstract : Glioblastoma multiforme is the most malignant primary brain tumor that affects adults, recognized by the World Health Organization as an aggressive grade IV astrocytoma. Patients diagnosed with this type of tumor are left with a poor prognosis even with the most advanced treatment available. READ MORE

  6. 15. Genetically engineered animals in future breeding programs

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Gro Hylén; [2016]
    Keywords : Genetically engineered animal; genome editing; transgenic animal; CRISPR Cas; ZFN; TALEN; breeding; foodproduction;

    Abstract : The purpose of this literature review is to investigate what genetically engineered animals are being used for and if genome editing is going to be a useful tool in future animal breeding. Genetically engineered animals have been used within the biomedical research field since the seventies. READ MORE