Essays about: "immunotherapy"

Showing result 16 - 20 of 45 essays containing the word immunotherapy.

  1. 16. Affibody phage display selections for lipid nanoparticle and affibody-mediated transient CAR T-cell therapy

    University essay from KTH/Proteinvetenskap

    Author : Tasnim Yasin Idris; [2022]
    Keywords : affibody; phage display; in vitro selection; CD5; CD8; CD19; CAR T-cell therapy.;

    Abstract : CAR T-cellbehandling är en immunterapi som har visat lovande resultat vid behandling av cancer. Trots det riktade immunsvaret som kan uppnås, betonar komplexiteten i tillverkningsprocessen och behandlingsproceduren det utrymme somm finns för förbättringar. READ MORE

  3. 17. Characterization of novel bispecific ADAPTs selected for cancer-related targets

    University essay from KTH/Proteinvetenskap

    Author : Blenda Hedin; [2021]
    Keywords : cancer therapy; alternative administration routes; ADAPT; ABD; protein technology; albumin; simultaneous bispecificity; CCL7; CEACAM5; VEGF-A;

    Abstract : Cancer is still one of the most common causes of death world-wide and in parallel there is a need to update the repertoire of therapies that withstand resistance of recurrent cancers. Since the introduction of antibody therapies as anti-cancer pharmaceuticals, recognized as immunotherapy in health care, it has been an increasing field in cancer therapy, as a more targeted treatment compared to chemotherapy. READ MORE

  4. 18. Formulation development of a recombinant VAR2-antiCD3 protein for cancer immunotherapy

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Maja Warlin; Frida Hallberg; [2021]
    Keywords : immunotherapy; cancer; pharmaceuticals; proteins; analytical techniques; molecular biotechnology; formulation; life science; engineering; pharmaceutical technology; Technology and Engineering;

    Abstract : The use of immunotherapy for treating cancer has received a lot of attention in the recent years. The therapy is based on activating or deactivating the patient’s own immune system to help fight the disease. One way of doing this, is using bispecific molecules that can target both cancer cells and T-cells simultaneously. READ MORE

  5. 19. Mathematical model for the change of the protein profiles in urine during the bladder cancer development

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Xin Wen; [2021]
    Keywords : bladder cancer; immunotherapy; pharmacodynamic model;

    Abstract : Most patients with bladder cancer are in the stage of non-muscle-invasive bladder cancer (NMIBC), while 30% of patients progress to the life-threatening muscle-invasive bladder cancer (MIBC) stage because of distant metastases. The selection of treatment options depends on the bladder cancer stage. READ MORE

  6. 20. Supervised Learning for Prediction of Tumour Mutational Burden

    University essay from KTH/Matematisk statistik

    Author : Joanna Hargell; [2021]
    Keywords : Supervised Learning; Tumour Mutational Burden; Generalized Linear Models; Decision trees; Support Vector Machines; statistik; tillämpad matematik; statistisk inlärning; mutationsbörda;

    Abstract : Tumour Mutational Burden is a promising biomarker to predict response to immunotherapy. In this thesis, statistical methods of supervised learning were used to predict TMB: GLM, Decision Trees and SVM. READ MORE