Essays about: "ligand-binding"

Showing result 1 - 5 of 18 essays containing the word ligand-binding.

  1. 1. Investigating ERβ chromatin binding and its potential interaction with LRH-1 in an ovarian context

    University essay from KTH/Proteinvetenskap

    Author : Mick Phenphak; [2023]
    Keywords : estrogen receptor beta; ovary; granulosa cells; ChIP; qPCR; östrogen receptor beta; äggstock; granulosa celler; ChIP; qPCR;

    Abstract : Invasiv äggstockscancer anses vara en av de mest dödligaste gynekologiska maligniteterna. Granulosacelltumör i äggstocken är en sällsynt subtyp av äggstockstumör, som utgör 1–5% av alla äggstockstumörer. De kan kännetecknas av den långsamma tillväxthastigheten och produktionen av höga östrogennivåer. READ MORE

  3. 2. Learning the shapes of protein pockets

    University essay from Göteborgs universitet/Institutionen för data- och informationsteknik

    Author : Alejandro Corrochano; Yossra Gharbi; [2022-10-14]
    Keywords : Protein; cavity; ligand-binding; 3D-equivariance; shape; latent space; e3nn; Fpocket; sc-PDB;

    Abstract : The comparison of protein pockets plays an important role in drug discovery. Through the identification of binding sites with similar structures, we can assist in finding hits and characterizing the function of proteins. Traditionally, the geometry of cavities has been described with scalar features, which are not fully representative of the shape. READ MORE

  4. 3. Screening of ligand binding behavior using a high-throughput method and development of guidelines for a learning material

    University essay from KTH/Lärande

    Author : Oscar Kornher; [2020]
    Keywords : Multimodal chromatography; screening experiments; high-throughput; PCA; learning material; focus group interviews; thematic analysis; crucial steps; coherence and interaction;

    Abstract : This study is comprised of two distinct parts, a chromatographic study and a didactic study.Chromatographic studyThe need for higher selectivity in chromatography purification has increased in recent years. Multimodal resins, offering novel selectivity, are a possible solution to this demand. READ MORE

  5. 4. BABAM1 regulation of NLRP3 inflammasome in THP-1 monocyte-like cell lines

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Musa Marrah; [2020]
    Keywords : ;

    Abstract : The nucleotide-binding oligomerization domain–like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a group of multi-protein complex that mediates immune responses through the production of biologically active IL-1β and IL-18. Dysregulation of NLRP3 inflammasome has been linked to various diseases associated with infection, inflammation, and cancer. READ MORE

  6. 5. Technology Development in the Field of Ligand Binding Assays : Comparison between ELISA and other methods

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Tanya Al-Khafaf; Björn Ancker Persson; Johanna Cederblad; Albert Häggström; Reneh Kostines; Lina Löfström; Ella Schleimann-Jensen; [2020]
    Keywords : ELISA; ligand binding assay; immunoassay; comparison; antibody;

    Abstract : .... READ MORE