Essays about: "multiplex"

Showing result 11 - 15 of 65 essays containing the word multiplex.

  1. 11. Functionalization and Evaluation of Nanoparticle Probes for the Development of a 14-Plex Diagnostic assay

    University essay from KTH/Kemi

    Author : Samuel Narmack; [2021]
    Keywords : Functionalization; multiplex; probing; diagnostics; nanoparticles; Funktionalisering; multiplexera; sonder; diagnostik; nanopartiklar;

    Abstract : Detta projekt var ett samarbete mellan Aplex Bio AB och Scilifelab. Projektets mål var att utveckla en molekylär diagnostisk panel med förmågan att detektera och diskriminera mellan 14 olika typer av patogener. Projektet innehåller 4 kapitel med fokus på olika mål. READ MORE

  2. 12. Validation and optimization of multiplexInSitu PLA for signalling pathway analysis

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Tanay Kumar Sinha; [2021]
    Keywords : Chronic myeloid leukemia Tyrosine kinase inhibitors Proximity ligation assay Cross-reactivity Padlock Template;

    Abstract : With the advent of Tyrosine kinase inhibitors (TKI) as a therapy for Chronic myeloid Leukemia (CML), the patients now enjoy a life expectancy close to that of the general population. But some patients do get unresponsive to the TKI treatment over time due to several mutations in the kinase domain of the BCR-ABL fusion protein, which further leads to activation of multiple signaling cascades within the leukemic cell, helping it survive and proliferate. READ MORE

  3. 13. Graph Complexity Based on a Heuristic That Involves the Algorithmic Complexity Behaviour of Multiplex Networks on Graphs

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Hasan Kalzi; [2021]
    Keywords : ;

    Abstract : Since determining the complexity of multiplex networks is an NP-hard problem, I decided to calculate the complexity of graphs using heuristics. I am the first in this path who did these kinds of calculations. I always wanted to define complexity as a mathematical characteristic in the structure of graphs. READ MORE

  4. 14. The fertile ovary transcriptome and proteome

    University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsa

    Author : Josephine Östman; [2021]
    Keywords : ovary; fertility; data analysis; gene expression; protein expression; immunohistochemistry;

    Abstract : The Human Protein Atlas is an open-source database containing information about protein expression and location in the human cells,tissues and organs. The aim is to map all the proteins in humans using various biotechnology techniques such as antibody-based imaging, andRNA sequencing etc. READ MORE

  5. 15. Subcellular mapping of cell types in healthy human pancreatic islets

    University essay from KTH/Proteinvetenskap

    Author : Frida Björklund; [2021]
    Keywords : Pancreatic islets; Multiplex tissue imaging; CODEX; DNA-conjugated antibodies; Spatial cell biology; Langerhanska öar; Multiplex mikroskopisk avbildning av vävnad; CODEX; DNA-konjugerade antikroppar; Spatial cellbiologi;

    Abstract : Pancreatic islets are composed of endocrine cells that secrete hormones essential for blood-glucose homeostasis. Prior research has revealed that the gene expression and functionality of human islet cells is heterogenous. READ MORE