Essays about: "Spatial cell biology"

Showing result 1 - 5 of 11 essays containing the words Spatial cell biology.

  1. 1. Chromatin accessibility analysis of spaceflight mouse brains using ArchR

    University essay from KTH/Genteknologi

    Author : Raphaël Mauron; [2023]
    Keywords : Single nuclei ATAC-sequencing; Space Biology; DNA Chromatin accessibility; Neurodegenerative; ArchR; ATAC-sekvensering av enskilda kärnor; rymdbiologi; tillgänglighet av DNA kromatin ; neurodegenerativa sjukdomar; ArchR;

    Abstract : Mänsklig utforskning av månen och Mars innebär stora utmaningar för människans fysiologi och hälsa på grund av de unika miljöfaktorer som följer av långvariga rymduppdrag. Rymdbiologiska experiment har blivit ett viktigt verktyg för att studera effekterna som mikrogravitation och rymdstrålning har på levande organismer, i syfte att förstå och minska dessa utmaningar. READ MORE

  3. 2. Modelling of gene regulatory and spatial mechanisms which pattern the early human neural tube

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Fredrik Bertilsson; [2022]
    Keywords : Biophysics; systems biology; gene regulatory networks; neural tube; isthmic organizer; midbrain-hindbrain boundary; WNT; FGF; morphogens; reaction-diffusion; finite-difference; 3D modelling; Physics and Astronomy;

    Abstract : Tissue patterning during development is thought to be driven largely by gene regulatory responses to spatial gradients of molecular signals, known as morphogens. In this thesis, early patterning of the human neural tube is studied using two different gene regulatory network models. READ MORE

  4. 3. Biophysical analysis of Immunotherapy and Cancer modeling

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Author : Simon Tropp; [2022]
    Keywords : Immunotherapy; Cancer; Tumors; Immune cells; T cells; Cancer prognostics; Cancer models; Cell distribution; Physics and Astronomy;

    Abstract : Accounting for 10 million deaths and 20 million new cases every year, cancer is one of the most common causes of death. The interest in trying to understand this lethal disease using mathematical models has increased steadily for many decades. Methods for boosting the immune system to better fight cancer (immunotherapy) have also been long present. READ MORE

  5. 4. Towards an understanding of the Retraction of TYPE IV PILI as a Mechanoresponse upon surface contact in Pseudomonas Aeruginosa

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Antoine Loussouarn; [2022]
    Keywords : Mechanosensing; Microscopy; Bacteria; Microfabrication; Genetics; Molecular Biology; Biophysics;

    Abstract : Pseudomonas Aeruginosa is an opportunistic bacterium which is involved in nosocomial infections and which causes increasing concern in healthcare due to its high antibiotic resistance. During an infection by P.aeruginosa, the bacteria proliferate in the host’s organism by leveraging motility abilities. READ MORE

  6. 5. Subcellular mapping of cell types in healthy human pancreatic islets

    University essay from KTH/Proteinvetenskap

    Author : Frida Björklund; [2021]
    Keywords : Pancreatic islets; Multiplex tissue imaging; CODEX; DNA-conjugated antibodies; Spatial cell biology; Langerhanska öar; Multiplex mikroskopisk avbildning av vävnad; CODEX; DNA-konjugerade antikroppar; Spatial cellbiologi;

    Abstract : Pancreatic islets are composed of endocrine cells that secrete hormones essential for blood-glucose homeostasis. Prior research has revealed that the gene expression and functionality of human islet cells is heterogenous. READ MORE