Essays about: "organisk syntes"

Showing result 11 - 15 of 18 essays containing the words organisk syntes.

  1. 11. Fragment screening using WAC towards new SMARCA4 inhibitors

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Artur Sahakjan; [2020]
    Keywords : WAC; Fragments; SMARCA4; Library; Fragment Based Drug Discovery FBDD ; Peptide Synthesis; Affinity; Organic chemistry; Organisk kemi; Chemistry;

    Abstract : The drug discovery and development process has changed dramatically during the last decades and the growth of more efficient techniques as high throughput screening combined with combinatorial synthesis using amino acids and carboxylic acids on solid support makes it possible to investigate the affinity of molecules towards a biological target. Fragment based drug discovery (FBDD) has been implemented into different techniques with purpose of discovering new drugs. READ MORE

  3. 12. Photoredox catalysis with 10-phenyl-10H- phenothiazine and synthesis of a photocatalytic chiral proline-based organocatalyst

    University essay from KTH/Organisk kemi

    Author : Panagiotis Lamprianidis; [2020]
    Keywords : organic chemistry; photocatalysis; organocatalysis; organocatalyst; organic synthesis; organisk kemi; fotokatalys; organokatalys; organokatalysator; organisk syntes;

    Abstract : Photoredox catalysis applications for the purpose of new synthetic routes in organic and sustainable chemistry are hot topics in organic synthesis today. In the present study, the synthesis of a chiral proline-based organocatalyst functionalized with 10-phenyl-10H phenothiazine (PTH) photocatalytic moietiesis investigated and attempted for the first time. READ MORE

  4. 13. SYNTHESIS OF β-D-RIBOPYRANOSIDES DERIVATIVES FROM β-D-XYLOPYRANOSIDE

    University essay from Lunds universitet/Kemiska institutionen

    Author : Christopher Musonda; [2018]
    Keywords : organic chemistry; organisk kemi; xylos; träsocker; proteoglykan; Chemistry;

    Abstract : The aim of this thesis was to synthesize various β-D-ribopyranoside derivatives with different C-4 functional groups, using D-xylose as the starting material. The desired modifications were deoxygenation, fluorination, methylation and epimerization of the C-4 hydroxyl group. READ MORE

  5. 14. Syntheses and Evaluation of Peptoids as Bioinert Coatings for Nanoparticles

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Christoffer Weber; [2018]
    Keywords : Peptoid; Antifouling; Polymer coating; Organic chemistry; Organisk kemi; Chemistry;

    Abstract : Polymers of N-substituted glycine (NSG) or as they are also called, peptoids, have shown potential in biomedical applications due to proteolytic resistance, among other interesting properties. In this thesis project, two synthetic routes have been performed and evaluated to achieve a better understanding of large-scale syntheses of peptoids as a bioinert coating for nanoparticles. READ MORE

  6. 15. Computational Design of an Enzyme-catalyzed Diels-Alder reaction

    University essay from KTH/Skolan för kemivetenskap (CHE)

    Author : Max Pettersson; [2016]
    Keywords : Diels-Alderase; Enzyme design; Catalysis; Computational chemistry; Molecular modelling;

    Abstract :    The Diels-Alder is an important reaction that is one of the primary tools for synthesizing cyclic carbon structures, while simultaneously introducing up to four stereocenters in the resulting product. Not only is it a widely explored reaction in organic chemistry, but a vital tool in industry to construct novel compounds for pharmacological applications. READ MORE