Essays about: "protein detection"

Showing result 11 - 15 of 132 essays containing the words protein detection.

1. 11. Study of surfactant-preservative and protein-preservative interactions in multi-dose injectable formulation

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

   Author : Javier Lagares Martín; [2023]
   Keywords : Phenol; polysorbate 80; cloud point; somatropin; aggregation; titration; light scattering; salt; surfactant; preservative; protein; tonicity adjusting agents; multi-dose injectable formulation; pharmaceutical technology; Technology and Engineering;

   Abstract : Multidose injectable formulations require a preservative such as phenol to ensure sterility and protection against microbial contamination during clinical use. However, it is known that the interaction between these components and non-ionic surfactants such as polysorbate 80, also found in this type of formulations, present incompatibilities, which can lead to decreases in the efficacy of the product. READ MORE

3. 12. Characterization of the immunomicroenvironment of glioblastoma : Optimization of an antibody panel for detection of glioblastoma TME cells and effect of C3 on glioma cells.

   University essay from Malmö universitet/Fakulteten för hälsa och samhälle (HS)

   Author : Julia Wahldén; [2023]
   Keywords : Brain; cancer; glioblastoma; immune cells; immunofluorescence; tumor microenvironment; Cancer; glioblastom; immunceller; immunofluorescens; hjärnan; tumörmikromiljö;

   Abstract : Glioblastoma (GBM) is the most common primary brain tumor in adults and represents one of the most aggressive tumor types. Despite treatment GBM remains incurable and when treated the tumor recurs more aggressive and treatment resistant than before. READ MORE

4. 13. Learning the shapes of protein pockets

   University essay from Göteborgs universitet/Institutionen för data- och informationsteknik

   Author : Alejandro Corrochano; Yossra Gharbi; [2022-10-14]
   Keywords : Protein; cavity; ligand-binding; 3D-equivariance; shape; latent space; e3nn; Fpocket; sc-PDB;

   Abstract : The comparison of protein pockets plays an important role in drug discovery. Through the identification of binding sites with similar structures, we can assist in finding hits and characterizing the function of proteins. Traditionally, the geometry of cavities has been described with scalar features, which are not fully representative of the shape. READ MORE

5. 14. Endothelial Protein C Receptor : Expression in the murine kidney

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Lina Molin; [2022]
   Keywords : Endothelial protein C receptor; murine kidney; murine kidney endothelial cells; glomerular cells; flow cytometry; western blot; dot blot; SDS-PAGE; murine kidney tissue;

   Abstract : This thesis aims to investigate if the endothelial protein C receptor is expressed in the murine kidney. This was done by performing flow cytometry and Western blot analysis on cultivated murine kidney endothelial cells (mKECs) as well as SDS-PAGE and Western blot analysis on murine kidney tissue. READ MORE

6. 15. Characterization of ulvan polysaccharide degrading enzymes from Wenyingzhuangia fucanilytica

   University essay from Lunds universitet/Bioteknik; Lunds universitet/Bioteknik (master)

   Author : Erik Apelqvist; [2022]
   Keywords : Enzyme; Enzymatic characterization; Recombinant protein producaiton; Protien purification; E. coli; W. fucanilytica; Transformation; Overexpression; Seaweed; Ulvan; Polysaccharides; biotechnology; Biology and Life Sciences;

   Abstract : The aim of this thesis was to fully characterize the enzyme WFp-105, including bioinformatic analysis, structural modeling, full activity and stability characterization and product determination. As well as for the enzyme WFp-37; optimize protein production in regard to expression strains and cultivation temperature, analyzing the genomic context as well as performing an initial activity detection. READ MORE