Essays about: "protein detection"

Showing result 6 - 10 of 132 essays containing the words protein detection.

  1. 6. Generation of a new ADAPT library for stability improvement

    University essay from KTH/Proteinvetenskap

    Author : Sumant Yogesh Salphale; [2023]
    Keywords : Phage display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; protein engineering; cancer detection; Fag-display; CEACAM5; EpCAM; Trop2; ADAPT; ABD; proteinteknik; cancerdetektion;

    Abstract : Under senare år har målinriktad terapi varit ett växande område inom cancerterapi som en mer målinriktad behandling än kemoterapi. Dessa behandlingar baseras främst på antikroppsbaserade läkemedel som är ganska stora och komplexa, vilket ökar den totala kostnaden för behandlingen. READ MORE

  3. 7. Detection and quantification of post-translational modifications in non-invasive samples : Phosphoproteins as biomarkers and a market analysis of protein quantification technologies

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Sammi Baudin; Hillevi Fjellström; Aron Kraft; Erica Lamberg; Måns Rosenbaum; Hanna Sjöstrand; [2023]
    Keywords : Phorphorylation; Proteomics; Biomarkers; Phosphoproteins; PTM; Amyotrophic lateral sclerosis; ALS; Alzheimer s disease; Parkinson s disease; Cancer; xMAP; SIMOA; NULISA; PEA; ELISA; Mass spectrometry; SomaScan;

    Abstract : Post-translational modifications (PTMs) of proteins can be a sign and/or cause of disease. These modified proteins have the potential to be used as biomarkers for diagnostic purposes. However, research in the field is limited. READ MORE

  4. 8. Development of a method to detect lysis and investigation if ozone has a lysing effect on Escherichia coli

    University essay from KTH/Proteinvetenskap

    Author : Klara Andrup; [2023]
    Keywords : Bacteremia; Ozone; Sepsis; Antibiotic resistance; Beta-galactosidase; Bakteriemi; Ozon; Sepsis; Antibiotikaresistans; Beta-galaktosidas;

    Abstract : Detta projekt genomfördes på företaget Sangair som för närvarande utvecklar medicinsk utrustning för att behandla bakteriemi med ozon. Bakteriemi uppstår när bakterier hamnar i blodomloppet, vilket kan trigga sepsis och septisk chock, med potentiellt dödligt utfall om obehandlat. READ MORE

  5. 9. Sensitive Detection of Blood Biomarker Pentraxin 3 – Development and Comparison of Amperometric and Capacitive Biosensors in Flow-Injection Systems

    University essay from Lunds universitet/Bioteknik; Lunds universitet/Bioteknik (master)

    Author : Viktor Johansson; [2023]
    Keywords : Bioanalysis; Pentraxin 3; PTX3; FIA; Flow-injection analysis; Sepis; Electopolymerization; Self-assembling monolayer; Amperometry; Capacitance; Biotechnology; Medicine and Health Sciences; Biology and Life Sciences; Technology and Engineering;

    Abstract : Within clinical diagnostics there is always a need for innovative methods that are rapid, sensitive, and more accurate. In this study two bioanalytical systems have been evaluated for pentraxin 3 (PTX3) detection. READ MORE

  6. 10. Optimization of two high-performance size-exclusion chromatography methods with diode-array detection for protein quantification and purity assessment

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Camilla Lane; [2023]
    Keywords : Method qualification; Protein concentration; Protein Purity; High Performance Size exclusion chromatography; Quality control; Analytical chemistry; Biology and Life Sciences;

    Abstract : Background: There is a need to develop methods of determining concentration and purity for two new affinity ligands, protein T and protein H, in order to ensure the quality of an industrial production of said proteins. Aims: To develop a High Performance Size Exclusion Chromatography, HPSEC, method to determine concentration and purity of protein T and to improve an existing HPSEC method for concentration and purity determination of protein H that show selectivity, display linearity between peak area and injection amount and give repeatable results. READ MORE