Essays about: "receptors"

Showing result 11 - 15 of 192 essays containing the word receptors.

  1. 11. Inflammatory Cell Infiltration and Expression of AT1 and AT2 Receptors in Angiotensin II and High-Salt Diet-Induced Balb/CJ Mice

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

    Author : Avishka Herat; [2023]
    Keywords : ;

    Abstract : Pulmonary oedema and pulmonary hypertension are often associated with heart failure. The Balb/CJ and C57BL/6J mouse strains have been shown to exhibit distinct genetic susceptibilities to heart failure. READ MORE

  3. 12. Identification of Immunological Targets for Brain Cancer Immunotherapy

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Zhenda Wang; [2022]
    Keywords : Cancer immunotherapy; brain cancer; neoantigen; MHC HLA; TCR;

    Abstract : Background Cancer immunotherapy has yielded many successes. Yet to some hard-to-treat brain tumors, such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), it still lacks substantial improvement. Neoantigens resulting from mutations in malignant cells are the key targets for employing adoptive cell therapies. READ MORE

  4. 13. Diffusion and Camera-Noise Modelling for Analysis of Single-Particle Tracking Movies

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Erik Clarkson; [2022]
    Keywords : reaction-diffusion; camera-noise modelling; single-particle tracking; Gillespie simulations; Physics and Astronomy;

    Abstract : Interactions between T-cells and other body cells is an essential part of the immune system. It involves the binding between surface receptors of the two cells. Specifically, T-cell receptors (TCRs) bind onto pMHC (peptide-loaded major histocompatibility complex) molecules on the partnering cell surface. READ MORE

  5. 14. Developing and validating assay-ready HEK-Blue CD40L cells : For a more flexible and faster screening of Affibody® molecules

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Erika Könberg; [2022]
    Keywords : cell biology; assay-ready cells; HEK-Blue cells;

    Abstract : Cell assay that evaluates a biologics’ potency and efficacy is an important part in the discovery and development of drug candidates. However, it requires regular maintenance of cell cultures, and the cell assays can only be performed when the cells have reached 70-80% confluency. READ MORE

  6. 15. The effects of IL-4 and IL-13 on human airway smooth muscle

    University essay from KTH/Proteinvetenskap

    Author : Sania Merchant; [2022]
    Keywords : Asthma; Airway hyperresponsiveness; Airway smooth muscle cells; Calcium flux; Dupilumab; Astma; luftvägshyperreaktivitet; glatta muskelceller från luftvägarna; kalciumflöde; dupilumab;

    Abstract : Typ 2-cytokiner, IL-4 och IL-13 är kända för att spela en viktig roll i airway hyperresponsiveness (AHR) eller luftvägshyperreaktivitet, där de glatta muskelcellerna (ASM) drar ihop sig för lätt och för mycket som svar på direkta eller indirekta stimuli. Detta gör AHR till en avgörande egenskap hos astmatiker. READ MORE