Essays about: "receptors"

Showing result 16 - 20 of 192 essays containing the word receptors.

  1. 16. Automated HER2 Scoring of Breast Cancer Tissue using Upconverting Nanoparticle Images

    University essay from Lunds universitet/Matematik LTH

    Author : Adam Belfrage; Alexander Wik; [2022]
    Keywords : HER2-scoring; image analysis; interpretability; digital pathology; computer aided pathology; whole slide imaging; ASCO-guidelines; singular value decomposition; shape models; Bayesian classification; Biology and Life Sciences; Medicine and Health Sciences; Technology and Engineering; Mathematics and Statistics;

    Abstract : Computer aided pathology is becoming more and more of a requirement within pathology due to increased demand of individualised treatments and personalised medicine. Because of the advance of digital pathology in recent years, where a high resolution camera acquire images of microscope slides, pathologists can now assess tissue samples in digital images. READ MORE

  3. 17. The impact of oral microbiota and other factors on taste perception

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Lisa Vasquez Johansson; [2022]
    Keywords : Mouth microflora; PROP-sensitivity; taste receptors; flavor; microbial composition; Smakperception; munnens mikroflora; smakuppfattning; smaklökar;

    Abstract : En mängd olika faktorer har visat sig påverka smakperceptionen. Ålder, fetma och den mikrobiellamiljön i munhålan är bara några exempel på omständigheter som kan resultera i smak-skillnader. READ MORE

  4. 18. Cellular localization of the estrogen receptor GPER1 in colorectal cancer cell lines

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Malin Lundvall; [2022]
    Keywords : colon cancer; GPER1; estrogen receptor; IF;

    Abstract : Colorectal cancer is the third most common cancer type in the world with a mortality rate of around 2000 people in Sweden, year 2018. Women tend to have a lower risk of developing and progressing colorectal cancer, specifically premenopausal women. This indicates that Estrogen plays an important role in protecting from colorectal cancer. READ MORE

  5. 19. Orphan G-Protein Coupled Receptors : Can we deorphanize the remaining orphans despite all the challenges?

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Micaela Andersson; [2022]
    Keywords : Deorphanization; Heterodimerization; High-throughput screening; Orphan G-protein Coupled receptor; Pseudogenes; Reversed pharmacology;

    Abstract : G-protein coupled receptors (GPCRs) play a key role in a broad range of biological processes by binding to a wide variety of signaling molecules, which have resulted in 34% of all FDA-approved drugs which target GPCRs. The human genome encodes for approximately 800 GPCR members of which about 140 non-olfactory receptors remain orphans with an unknown function and endogenous ligand. READ MORE

  6. 20. The differential signalling of the succinate receptor SUCNR1/GPR91, through Gi versus Gq

    University essay from Lunds universitet/Teknisk mikrobiologi

    Author : Sofie Liljewall; [2022]
    Keywords : GPR91; SUCNR1; G protein recruitment; Gi; Gq; TRUPATH biosensor; BRET2; Applied Microbiology; Biology and Life Sciences;

    Abstract : G protein-coupled receptors are the biggest family of membrane bound receptor in the human genome, they are also target for many drugs due to their accessible location in the cell membrane. We have characterized the G protein recruitment of the succinate receptor 1 (SUCNR1/GPR91). READ MORE