Essays about: "rna-seq"

Showing result 11 - 15 of 33 essays containing the word rna-seq.

  1. 11. Detection of aberrant events in RNA for clinical diagnostics

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Mei Wu; [2021]
    Keywords : rare; disease; clinical; bioinformatics; pipeline; analysis; variants; IDS; OPA3; wgs; transcriptome; rna; diagnosis;

    Abstract : Rare diseases are estimated to affect 3.75% of the global population, which roughly translates to 300 million affected individuals. READ MORE

  3. 12. Explorative bioinformatic analysis of cardiomyocytes in 2D &3D in vitro culture system

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Sruthy Janardanan; [2021]
    Keywords : Cardiomyocytes; Pluripotent stem cells; 2D; 3D; differentially expressed genes; Hub nodes; Hub-Bottleneck nodes;

    Abstract : The in vitro cell culture models of human pluripotent stem cells (hPSC)-derived cardiomyocytes (CMs) have gained a predominant value in the field of drug discovery and is considered an attractive tool for cardiovascular disease modellings. However, despite several reports of different protocols for the hPSC-differentiation into CMs, the development of an efficient, controlled and reproducible 3D differentiation remains challenging. READ MORE

  4. 13. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ojong Tabi Ojong Besong; [2021]
    Keywords : ;

    Abstract : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. READ MORE

  5. 14. Dual RNA-seq analysis of host-pathogen interaction in Eimeria infection of chickens

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Arnar Kári Sigurðarson Sandholt; [2020]
    Keywords : Dual RNA-seq; Bioinformatics; Eimeria tenella; Gene co-expression networks; Chicken;

    Abstract : Eimeria tenella is a eukaryotic, intracellular parasite that, along with six other Eimeria species, causes coccidiosis in chickens. This disease can result in weight loss or even death and is estimated to cause 2 billion euros of damages to the chicken industry each year. While much is known of the life cycle of E. READ MORE

  6. 15. Analysis of differentially expressed genes (DEGs) in neuronal cells from the cerebral cortex of Alzheimer’s disease mouse model

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Elnaz Bakhtiyari; [2020]
    Keywords : ;

    Abstract : Alzheimer’s disease (AD) is an aging-related neurodegenerative disorder with large implications for society and individuals. AD is a multi-factor disorder, with these factors having a direct or indirect correlation with each other. READ MORE