Essays about: "tuberculosis treatment"

Showing result 1 - 5 of 22 essays containing the words tuberculosis treatment.

  1. 1. Can Feeding Amyloid Fibrils Trigger Amyloid Formation in C. Elegans?

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Katarina Norrby; [2023]
    Keywords : Amyloid; AA amyloid; Amyloidosis; AA amyloidosis; C. Elegans;

    Abstract : Amyloidosis are diseases caused by misfolded proteins that have transformed into extracellular insoluble amyloid fibrils. One type of amyloidosis is AA amyloidosis caused by AA amyloid and diseases connected are Rheumatoid arthritis and Tuberculosis. C. Elegans is a nematode used as a model organism and in this experiment. READ MORE

  3. 2. Evaluation of antimycobacterial molecules' capacity to kill mycobacteria and their toxic effect on human cells.

    University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Author : Filippa Henriksson; [2023]
    Keywords : Drug evaluation; In vitro; Mycobacterium tuberculosis complex; REMA; Tuberculosis; In vitro; Mycobacterium tuberculosis complex; REMA; tuberkulos; utvärdering av läkemedel;

    Abstract : Tuberculosis is a fatal airborne disease caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). The incidence of contracting tuberculosis is estimated to be around 10.6 million cases each year. Increased drug resistance among mycobacteria has led to the need to develop new treatments. READ MORE

  4. 3. Population Pharmacokinetics of Linezolid for Optimization of the Treatment for Multidrug Resistant Tuberculosis

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Viktor Hansen; [2022]
    Keywords : tuberculosis; drug resistance; pharmacometrics; pharmacokinetics; pop-pk; south africa; non linear mixed effects modelling; nlme;

    Abstract : Tuberculosis is one the leading causes of death globally and was before the COVID-19 pandemic the leading cause of death from a single infectious agent. Developing active tuberculosis is life threatening and therefore is the rise of drug-resistant tuberculosis alarming as this risk causing current treatments to become ineffective. READ MORE

  5. 4. Understanding the spatial elements at the tuberculosis sanatoria in Sweden: 1887-1942 : Cartography and spatial interpretation through geography information systems (GIS)

    University essay from Uppsala universitet/Institutionen för ABM

    Author : Elisa Serrano; [2021]
    Keywords : Sanatoria; Tuberculosis; Spatial Analysis; GIS; Hermeneutics of Space; Social Cartographies; Sanatorios; Tuberculosis; Análisis Espacial; SIG; Hermeneútica del Espacio; Cartografías sociales;

    Abstract : This project aspires to understand the tuberculosis sanatoria in Sweden from the perspective of their location in space and the interpretation of the characteristics of their landscapes. The study has sorted the areas of analysis in the following categories: [i] distribution, [ii] altitude, [iii] orientation, [iv] proximity to the sea, [v] proximity to lakes or rivers, [vi] proximity to train stations, [vii] proximity to forests, [viii] proximity to towns or hospitals, [ix] proximity to industries. READ MORE

  6. 5. Optimized design recommendation for first pharmacokinetic in vivo experiments for new tuberculosis drugs using pharmacometrics modelling and simulation

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Albin Leding; [2021]
    Keywords : Pharmacokinetics; Pharmacometrics; Pharmacology; population pharmacokinetics; physiologically-based pharmacokinetics; in vitro to in vivo extrapolation; IVIVE; PBPK; PK; popPK; tuberculosis; model informed approach; first in vivo pharmacokinetic experiment; mouse; mice; PKSim; NONMEM; in vitro; in vivo;

    Abstract : Tuberculosis, the leading cause of death by a single infection disease caused by bacteria, requires long treatments and the bacteria are prone to develop drug resistance. Therefore, new efficient treatment regiments needs developing, which requires new tools for drug development. READ MORE