Dataset based on volunteer campaign to optimize novel sensor for muscle quality

University essay from Uppsala universitet/Fasta tillståndets elektronik

Author: Sophia Holmqvist; [2022]

Keywords: sarcopenia; microwaves; medical imaging;

Abstract: This project had its primary focus on running a campaign to recruit healthy volunteers for a test study involving the utilization of a microwave sensor and ultrasound measurements. The key system used was the Muscle Analyzer System (MAS), which consisted of the Bandstop Filter Sensor (BFS), a microwave sensor transmitting microwaves into the selected medium through transmission and a FieldFox Vector Network Analyzer which was used to transmit these microwaves. The second system utilized in the project was ultrasound imaging, which enabled the measurement of the size of the Rectus Femoris muscle in the thigh and the thickness of the fat and skin layers on the volunteer. This information served as a basis for interpreting the resonant frequency obtained from the MAS system. The goal was to compare these results to assess the muscle quality of the volunteers. A total of nine volunteers participated in the study, with data from four volunteers being suitable for follow- up data analysis and further research. The primary method used to obtain these results involved collecting measurements from the volunteers and comparing them with results from previous measurements conducted on sick patients in Maastricht. The resonant frequency observed for the volunteers in Uppsala was approximately 2.15 GHz, with the fat layer ranging from 5 to 18 mm in thickness, the skin layer measuring 2 mm thick, and the Rectus Femoris muscle having an area of 4 to 8 cm2. When these measurements were compared with the measurements from Maastricht on sick patients, a significant difference was observed. The patients' measurements showed values of approximately 1.98 GHz, even though there wasn't a substantial difference in the muscle and fat layer areas. In order to draw meaningful conclusions however, it would be necessary to conduct measurements using the same Vector Network Analyzer (VNA) for both healthy volunteers and sick patients with sarcopenia.

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