Essays about: "Artemisinin"

Showing result 1 - 5 of 6 essays containing the word Artemisinin.

  1. 1. Novel Therapy against Malaria Resistance using Meta-analysis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Adesola Oguntuyi; [2022]
    Keywords : Malaria; Novel Drug; Resistance; ACT;

    Abstract : Malaria causes severe illness and death in some cases if not treated on time. The most vulnerable people are children and pregnant women in areas where it is rampant. The causative agent of the most severe malaria is Plasmodium falciparum this parasite is transmitted by the female anopheles mosquito when infected with Plasmodium parasites. READ MORE

  3. 2. Characterisation of Potential Inhibitors of Calmodulin from Plasmodium falciparum

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Alexandra Iversen; Ebba Nordén; Julia Bjers; Filippa Wickström; Martin Zhou; Mohamed Hassan; [2020]
    Keywords : Plasmodium falciparum; Calmodulin; Malaria; Trifluoperazine; Calmidazolium; Artemisinin; Fentanyl derivatives; Modelling; Docking; Bioinformatics;

    Abstract : Each year countless lives are affected and about half a million people die from malaria, a disease caused by parasites originating from the Plasmodium family. The most virulent species of the parasite is Plasmodium falciparum (P. falciparum). READ MORE

  4. 3. Assessing the efficacy of artemisinin-based combination therapies (ACTs) against Plasmodium malariae and Plasmodium ovale infections with low parasite densities: overcoming challenges during molecular analyses

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Ioanna Broumou; [2020]
    Keywords : Malaria; Plasmodium malariae; Plasmodium ovale; low density infections; PCR detection;

    Abstract : Background: Malaria is a major public health issue. Artemisinin-based combination therapies are the WHO recommended treatment for uncomplicated malaria. Plasmodium malariae and Plasmodium ovale infections are considered underestimated and the effectiveness of artemisinin-based combination treatments against them is poorly documented. READ MORE

  5. 4. Treatment efficacy of artesunate-amodiaquine and prevalence of Plasmodium falciparum drug resistance markers in Zanzibar, 2002-2017

    University essay from Uppsala universitet/Internationell mödra- och barnhälsovård (IMCH)

    Author : AUNG PAING SOE; [2019]
    Keywords : Plasmodium falciparum; Artesunate-amodiaquine; Therapeutic efficacy studies; Molecular surveillance; Antimalarial drug resistance;

    Abstract : Introduction: Emergence of resistance to artemisinin-based combination therapy (ACT) is a major threat to combat Plasmodium falciparum malaria. Regular therapeutic studies to monitor treatment efficacy is essential, and genotyping of molecular makers is useful for mapping development and spread of resistance. READ MORE

  6. 5. Synthesis of novel PfDHODH inhibitors based on 4-aminocoumarin structures

    University essay from Lunds universitet/Kemiska institutionen

    Author : Federico Valerio; [2016]
    Keywords : PfDHODH; coumarins; synthesis; medicinal chemistry; inhibitors; Malaria; organic chemistry; organisk kemi; Chemistry;

    Abstract : Malaria is an infectious disease caused by the protozoan of the genus Plasmodium. It is a major problem in third-world countries, with hundreds of millions of infections and millions of fatalities annually. The extreme challenge in malaria management is the resistance of parasites to traditional chemotherapies like chloroquine and artemisinin. READ MORE