Essays about: "Biological drugs"

Showing result 16 - 20 of 44 essays containing the words Biological drugs.

1. 16. Improving ligand-based modelling by combining various features

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Abir Omran; [2021]
   Keywords : Machine learning; QSAR; Support Vector Machine; Morphological Profiles; Conformal Prediction;

   Abstract : Background: In drug discovery morphological profiles can be used to identify and establish a drug's biological activity or mechanism of action. Quantitative structure-activity relationship (QSAR) is an approach that uses the chemical structures to predict properties e.g., biological activity. READ MORE

3. 17. A high-throughput method for screening of protein binding behavior of multimodal anionic exchange ligands

   University essay from Uppsala universitet/Analytisk farmaceutisk kemi

   Author : Ani Avedis; [2021]
   Keywords : Multimodal chromatography; multimodal anionic exchange ligands; product development; purification process; biological drugs; resins;

   Abstract : The biopharmaceutical industry is constantly developing biological drugs, resulting in increased levels of product related impurities having similar characteristics as the target. The aim of the ligand project was to address future challenging purifications by developing new ligands for future resins for the biopharmaceutical industry. READ MORE

4. 18. The Effect of Chemotherapy Treatment on Bone Marrow Mesenchymal Stromal Cell Adipocyte Differentiation

   University essay from KTH/Proteinvetenskap

   Author : Hanna Andersson; [2021]
   Keywords : Acute lymphoblastic leukaemia; Doxorubicin; Dexamethasone; Stromal cell fat differentiation; cytokines; Akut lymfatisk leukemi; Doxorubicin; Dexametason; stromacellers fettdifferentiering; cytokiner;

   Abstract : I ett försök att förstå orsakerna bakom de kardio-, metaboliska- och muskuloskeletala sjukdomar hos barn som överlevt akut lymfatisk leukemi (ALL) har vi studerat den adipogena differentieringen hos mesenkymala stromaceller från benmärg (BM MSCs). Det komplexa nätverket av faktorer som påverkar adipogenes är hittills inte helt kartlagt. READ MORE

5. 19. Development of a reporter gene assay on an automated platform

   University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

   Author : Fanny Redin; [2021]
   Keywords : Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

   Abstract : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. READ MORE

6. 20. The Effect of Chemotherapy Treatment on Bone Marrow Mesenchymal Stromal Cell Adipocyte Differentiation

   University essay from KTH/Proteinvetenskap

   Author : Hanna Andersson; [2021]
   Keywords : Acute lymphoblastic leukaemia; Doxorubicin; Dexamethasone; Stromal cell fat differentiation; cytokines; Akut lymfatisk leukemi; Doxorubicin; Dexametason; stromacellers fettdifferentiering; cytokiner;

   Abstract : I ett försök att förstå orsakerna bakom de kardio-, metaboliska- och muskuloskeletala sjukdomar hos barn som överlevt akut lymfatisk leukemi (ALL) har vi studerat den adipogena differentieringen hos mesenkymala stromaceller från benmärg (BM MSCs). Det komplexa nätverket av faktorer som påverkar adipogenes är hittills inte helt kartlagt. READ MORE