Essays about: "Biological drugs"
Showing result 11 - 15 of 44 essays containing the words Biological drugs.
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11. Orphan G-Protein Coupled Receptors : Can we deorphanize the remaining orphans despite all the challenges?
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologiAbstract : G-protein coupled receptors (GPCRs) play a key role in a broad range of biological processes by binding to a wide variety of signaling molecules, which have resulted in 34% of all FDA-approved drugs which target GPCRs. The human genome encodes for approximately 800 GPCR members of which about 140 non-olfactory receptors remain orphans with an unknown function and endogenous ligand. READ MORE
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12. Development of a novel quantitative PCR analysis method for HIV-1
University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/BeräkningskemiAbstract : Biological pharmaceuticals are the answer to many severe diseases of today’s society. Some of these are protein-based drugs and can be produced from human blood plasma. In order to guarantee the safety of patients, absence of any pathogens needs to be ensured. READ MORE
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13. Predicting safe drug combinations with Graph Neural Networks (GNN)
University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskapAbstract : Many people - especially during their elderly - consume multiple drugs for the treatment of complex or co-existing diseases. Identifying side effects caused by polypharmacy is crucial for reducing mortality and morbidity of the patients which will lead to improvement in their quality of life. READ MORE
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14. Temporal Multivariate Distribution Analysis of Cell Shape Descriptors
University essay from Umeå universitet/Institutionen för fysikAbstract : In early drug discovery and the study of the effects of new chemical compounds on cancer cells, the change in cell shape over time provides vital information about cell health. Live-cell image analysis systems can be used to extract cell-shape describing parameters of individual cells during exposure to new drugs. READ MORE
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15. Expression & affinity analysis of recombinant RX against pathogenic α-synuclein
University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskapAbstract : Background In the as of yet uncurable Parkinson´s disease aggregation of α-syn is an accelerator of pathogenesis. Oligomers of α-synuclein is considered to be neurotoxic hence blocking the endocytosis of aggregated α-syn is possibly a way of preventing pathogenesis. READ MORE