Essays about: "Cancer mutations"

Showing result 21 - 25 of 50 essays containing the words Cancer mutations.

  1. 21. Investigating correlations between chemical connectivity patterns and cancer mutations using machine learning

    University essay from Uppsala universitet/Avdelningen för systemteknik

    Author : Gustav Lind; [2021]
    Keywords : ;

    Abstract : Proteins are a group of naturally occurring, highly versatile organic macromolecules which can perform a wide range of biological functions in living systems by folding into complex three-dimensional shapes. This thesis project deploys data science and machine learning methods in the study of protein structures with the aim to better the knowledge of the relation between structural and chemical properties of proteins and cancer mutations observed in humans. READ MORE

  3. 22. Cost-Effectiveness of Surveillance Programs of Carriers of Pathogenic Mutations in the TP53-Gene in Sweden

    University essay from Linköpings universitet/Nationalekonomi

    Author : Oskar Frisell; [2020]
    Keywords : TP53 Surveillance Cost-effectiveness Genetics;

    Abstract : Introduction: Pathogenic mutations in the TP53-gene is present in about 50% of all somatic cancers. The TP53 gene’s function is to stop cancer cells from dividing, thus protect us from cancer. When this gene is not functioning properly, carriers face 70-100% risk of developing cancer in their lifetime. READ MORE

  4. 23. Oncologists´ perspectives and practice on exogenous reproductive hormone use in breast cancer patients

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Sofie Nisbeth; [2020]
    Keywords : ;

    Abstract : Purpose: the study aimed to investigate oncologists´ perspectives and practices on their prescription of oral hormonal contraceptives (OHC), menopausal hormone therapy (MHT) and local estrogen therapy in patients with prior breast cancer diagnosis or BRCA-mutation carriers. Method: The study was a web-based survey, based on fictional patient cases that was sent out to 134 breast oncologists in Sweden. READ MORE

  5. 24. DNA damage – a novel method to measure the rate of single-stranded breaks from fragmenting dsDNA in nanochannels – theory and modeling

    University essay from Lunds universitet/Fysiska institutionen; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Magnus Brander; [2020]
    Keywords : biophysics; DNA damage; single-stranded breaks; double-stranded breaks; Bayesian inference; Brownian motion; Gillespie algorithm; photosensitized DNA damage; Physics and Astronomy;

    Abstract : Damage to DNA can cause death to an individual cell and serious harm to the host organism. Photosensitized reactions are one cause of DNA damage. It can lead to destructive chemical reactions targeted to a base of the DNA as well as a breakage along one or both of the DNA strands. READ MORE

  6. 25. Deciphering the ontogeny of unmutated and mutated subsets of Chronic Lymphocytic Leukemia

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ahmed Mohamed; [2019]
    Keywords : CLL; NGS; mutated CLL; unmutated CLL; CD27 bright; CD27 dull; memory B cell; RNA-sequencing;

    Abstract : Chronic Lymphocytic Leukemia (CLL) is a type of cancer that affects the B cells of the immune system causing problems in the process of producing antibodies. It can be sorted into mutated and unmutated CLL based on the percentage of somatic mutations in the Immunoglobulin Heavy chain Variable region (IgHV). READ MORE