Essays about: "GABAA receptor"
Found 3 essays containing the words GABAA receptor.
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1. Computational Modeling and Characterization of the Human Tri-Heteromeric GABAA Receptor
University essay from KTH/Tillämpad fysikAbstract : -aminobutyric acid receptors of type A (GABAARs) are the majorinhibitory neurotransmitter receptors in the human brain, andare modulated by a vast range of exogenous molecules, such assedatives and anesthetics. In the last year, the first cryo-electronmicroscopy (cryo-EM) images of the closed and desensitized statesof the GABAAR were released, enabling fruitful research throughsimulations of these complex proteins. READ MORE
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2. Characterization of the binding of the novel compound GT-002 to GABAA receptors in the mammalian brain : Development and validation of a radioligand binding assay. A comparative study to Flumazenil
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologiAbstract : Gamma-Amino butyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system (CNS) and inhibits the neurotransmission by targeting the ionotropic transmembrane GABAA receptor. Modulators of the GABAA receptor targets the allosteric binding sites and modifies the GABA effect and these sites acts as superior drug targets within psychopharmacology. READ MORE
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3. Premenstrual Dysphoric Disorder : A Review of Neural and Cognitive Changes in Women with PMDD
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Around 3-8% of all women in reproductive age suffer from premenstrual dysphoric disorder (PMDD) which disenables them to live an ordinary life during the luteal phase (premenstrual phase) of the menstrual cycle. Throughout the premenstrual phase these women experience emotional, cognitive and physiological changes. READ MORE