Essays about: "Imatinib"

Found 3 essays containing the word Imatinib.

1. 1. Prognostic Factors for 12 Month Major Molecular Response for Patients with Chronic Myeloid Leukemia

   University essay from Statistiska institutionen

   Author : Jonas Höijer; [2013]
   Keywords : Chronic Myeloid Leukemia; CML; Major Molecular Response; MMR; Prognostic factors; Logistic regression; Statistical modelling;

   Abstract : Chronic Myeloid Leukemia is a kind of blood cancer with around 1 incidence per 100 000 persons/year. After the development of an effective treatment, imatinib, in the late 1990:s, the survival percentage has increased drastically. READ MORE

3. 2. Development of a quantitative chromatographic method for the determination of Imatinib and its main metabolite in human plasma

   University essay from Institutionen för fysik, kemi och biologi

   Author : Paulina Hillberg; [2009]
   Keywords : Imatinib; HPLC-UV; LC-MS; analytical chemistry; CML;

   Abstract : The objective of this master thesis was to develop an analytical method for the quantification of the cancer drug Imatinib and its main metabolite CGP74588 in plasma. Imatinib is used in the treatment of chronic myeloid leukemia and gastrointestinal stroma tumors. READ MORE

4. 3. Adjuvant and Down-Staging Treatment with Imatinib in Gastrointestinal Stromal Tumours

   University essay from Hälsouniversitetets läkarutbildning

   Author : Anna Andersson; [2008]
   Keywords : GIST; imatinib; adjuvant; down-staging; neoadjuvant; mutation; KIT; PDGFRA;

   Abstract : Background: GISTs are gastrointestinal mesenchymal tumours that express the type III receptor tyrosine kinase KIT. The KIT proto-oncogene encodes the receptor KIT. Most GISTs have gain-of-function mutations in the KIT or PDGFRA gene. The tyrosine kinase is therefore continuously activated leading to ligand-independent dimerization. READ MORE