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Found 1 essay matching the above criteria.

1. 1. Immunostimulatory DNA : studies on the importance of secondary structure formation and CpG-motifs for IFN-alpha induction/inhibition using ODNs related to the genome of porcine circovirus type 2

   University essay from SLU/Dept. of Molecular Biosciences

   Author : Josefine Elving; [2006]
   Keywords : interferon; porcine circovirus; PCV-2; CpG; secondary structure; inhibitory; PCR; ODN;

   Abstract : Nucleotide sequences containing CpG-motifs are recognized as immunomodulators in pigs among other species. Phosphodiester oligodeoxynucleotides (ODNs), such as ODN H, have been demonstrated to be potent inducers of interferon-alpha (INF-alpha) in porcine blood mononuclear cells (poPBMC) provided they are pre-treated with Lipofectin®. READ MORE