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Showing result 6 - 10 of 14 essays matching the above criteria.

  1. 6. Prediction of hub miRNAs and their associated pathways in Alzheimer's disease with miRNA-mRNA-TF network using bioinformatic tools

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Monika Kumari; [2021]
    Keywords : ;

    Abstract : The prevalence of Alzheimer’s in Europe is increasing strikingly over the past decade. Addressing this neurodegenerative disorder can be arduous as the underlying cause isn’t often reversible. READ MORE

  3. 7. Exhibiting transparency without opening the 'Black Box' - Balancing act between Data Protection and Trade Secrets Rights in Solely Automated Decision-Making AI system in Healthcare

    University essay from Lunds universitet/Juridiska institutionen; Lunds universitet/Juridiska fakulteten

    Author : Kristina Christensen; [2020]
    Keywords : Artificial Intelligence; Healthcare; Automated Decision-Making; Transparency; Data Protection; GDPR; Trade Secrets; TSA; Balancing Act; Law and Political Science;

    Abstract : What was once called science fiction has developed over the years to be one of the most strategic technologies of the 21st century – artificial intelligence (AI) is real. The rapid digitalization has opened new pathways in Swedish healthcare, by increasing productivity and the effectiveness of care delivery as well as helping more patients in receiving better care. READ MORE

  4. 8. Utilization of cancer-specific genome-scale metabolic models in pancreatic ductal adenocarcinomas for biomarkers discovery and patient stratification

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Mohamed Al Shobky; [2019]
    Keywords : Genome-Scale Metabolic Models; GEM; Pancreatic Ductal Adenocarcinomas; pancreatic cancer; cancer metabolism; biomarker; LDHA; L-lactate dehydrogenase A chain;

    Abstract : Pancreatic Ductal Adenocarcinomas initiates in the exocrine part of the pancreatic tissue and represents over 90% of all the pancreatic cancers. Pancreatic Ductal Adenocarcinomas are extremely aggressive and are one of the most lethal malignant neoplasms. The five-year relative survival is currently less than 8% of the patients. READ MORE

  5. 9. Identification of personalized multi-omic disease modules in asthma

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : David Martínez Enguita; [2018]
    Keywords : modules; asthma; personalized; systems biology; molecular biology; transcriptomics; genomics; networks; disease; biomarker; microarray; individualized; endotype; phenotype;

    Abstract : Asthma is a respiratory syndrome associated with airflow limitation, bronchial hyperresponsiveness and inflammation of the airways in the lungs. Despite the ongoing research efforts, the outstanding heterogeneity displayed by the multiple forms in which this condition presents often hampers the attempts to determine and classify the phenotypic and endotypic biological structures at play, even when considering a limited assembly of asthmatic subjects. READ MORE

  6. 10. Mitochondrial DNA as a danger-associated molecular pattern in Myalgic encephalitis and endometrial cancer

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Nilsson Isabell; [2018]
    Keywords : Myalgic encephalitis; chronic fatigue syndrome; endometrial cancer; mitochondrial DNA;

    Abstract : Mitochondria are complex organelles, which are involved in various important metabolic pathways. Due to their proteobacterial evolutionary origin, the mitochondria DNA resemble unmethylated microbial CpG motifs, which possess the ability to interact with pathogen associated DNA sensors, such as TLR9 and activate the NLRP3 inflammasome, inducing pro- inflammatory cytokines. READ MORE