Essays about: "Single-cell genomics"
Found 4 essays containing the words Single-cell genomics.
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1. Regulatory Driven Clustering of Single-Cell Data; Clustering of single-cell RNA sequencing from glioblastoma with a novel mathematical method
University essay from Göteborgs universitet/Institutionen för matematiska vetenskaperAbstract : Cancer is a leading cause of death worldwide. Single-cell RNA sequencing has arisen as an important method to explore the gene expression of biological cells, including cancer cells. In this study, we deployed a computational algorithm known as ScRegClust to dissect single-cell RNA-sequencing (scRNA-seq) data from brain tumors. READ MORE
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2. Image-Based Classification Solutions for Robust Automated Molecular Biology Labs
University essay from KTH/Medicinteknik och hälsosystemAbstract : Single-cell genomics (SCG) are methods for investigating heterogeneity between biological cells, among these is Smart-seq which sequences from RNA molecules. A more recent version of this method is Smart-seq3xpress which is currently in the process of being automated by the Sandberg lab at Karolinska Institutet. READ MORE
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3. Single-cell RNA-seq mapping of chicken leukocytes : An investigation into single-cell transcriptomics as an alternative to traditional immunological methods within non-traditional model organisms
University essay from Uppsala universitet/Mikrobiologi och immunologiAbstract : The immune system is a complex infrastructure where many cells interact with each other and perform duties depending on their type and function. When using traditional immunological methods in studying non-traditional model organisms, such as birds, challenges arise. READ MORE
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4. The role of RFX-target genes in neurodevelopmental and psychiatric disorders
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Neurodevelopmental disorders such as autism spectrum disorder (ASD) and psychiatric disorders, for example, schizophrenia (SCZ) represent a large spectrum of disorders that manifest through cognitive and behavioural problems. ASD and SCZ are both highly heritable, and some phenotypic similarities between ASD and SCZ have sparked an interest in understanding their genetic commonalities. READ MORE