Essays about: "TNF-"

Showing result 1 - 5 of 45 essays containing the word TNF-.

  1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Sam Vadi Dris; [2024]
    Keywords : Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

    Abstract : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. READ MORE

  2. 2. Expression of complement factor C1r and C1s in human gingival fibroblasts

    University essay from Umeå universitet/Institutionen för odontologi

    Author : Hanna From; [2023]
    Keywords : fibroblasts; pEDS; C1r; C1s;

    Abstract : Background: Periodontitis is an inflammatory condition rendering in degradation of tooth supporting tissue. In the inflammatory process cytokines, amongst others TNF-a, IL-1b and IL-6 play an important role in regulating the immune response. READ MORE

  3. 3. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model

    University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Author : Emilie Allentoft Schousboe; [2023]
    Keywords : 3D models; imiquimod; Langerhans cells; MUTZ-3 cell line; pro-inflammatory cytokines; psoriasis;

    Abstract : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. READ MORE

  4. 4. Testing Coagulation Potential of Extracellular Vesicles Derived from Aortic Stenosis Patients on Human Cardiac Spheroids

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Muhammad Nafiz Ikhwan Bin Nor Fuad; [2023]
    Keywords : Extracellular vesicles; human aortic endothelial cells; tissue factor; TNFα; coagulation pathway; cardiac spheroids;

    Abstract : Cardiovascular diseases have always been the leading cause of global morbidity and mortality. Aortic stenosis, which is a kind of cardiovascular disease has a high prevalence in elderlies that are 75 years and older. Currently, the only available treatment would be valve replacement surgery. READ MORE

  5. 5. Determine how estrogen and TNFα impact circadian clock genes in colorectal cancer (CRC) cells

    University essay from KTH/Proteinvetenskap

    Author : Linnéa Lindquist; [2023]
    Keywords : colorectal cancer; gut microbiome; whole genome analysis; estrogen; high-fat diet; kolorektalcancer; magmikrobiom; helgenomanalys; östrogen; högfettsdiet;

    Abstract : Kolorektalcancer är den tredje vanligaste cancerformen i världen. Hormonet östrogen har visat sig ha skyddande effekter och i tjocktarmen förmedlas dess effekt av östrogenreceptorn β (ERβ). READ MORE