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1. 1. Integrative analysis of age-related changes in the transcriptome of Caenorhabditis elegans

   University essay from Högskolan i Skövde/Institutionen för biovetenskap; Högskolan i Skövde/Forskningscentrum för Systembiologi

   Author : Tsimafei Padvitski; [2015]
   Keywords : Aging; gene expression; RNA-seq; transcription regulation;

   Abstract : Ageing is difficult to study because of the complexity and multi-factorial nature of traits that result from a combination of environmental, genetic, epigenetic and stochastic factors, each contributing to the overall phenotype. In light of this challenge, transcriptomic studies of aging organisms are of particular interest, since transcription is an intermediate step that links genotype and phenotype. READ MORE