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Showing result 1 - 5 of 9 essays matching the above criteria.

1. 1. Characterisation and Identification of Human Mesenchymal Stromal Cells and the Impact of Different Culturing Media

   University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

   Author : Sana Said Yahya; [2023]
   Keywords : Culturing media; Fetal bovine serum; Human serum; Cell proliferation; In-vitro differentiation;

   Abstract : Background: Mesenchymal stromal cells (MSCs) are multipotent cells that can differentiate into various cell types and possess immunomodulatory and anti-inflammatory effects, making them interesting candidates for therapeutic applications. MSCs are present in small quantities in tissues like bone marrow and therefore need to be expanded while preserving their essential characteristics. READ MORE

3. 2. Identification of Human Mesenchymal Stromal Cells and Culturing Media Effects on Proliferation, Differentiation, and Cell Surface Markers

   University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

   Author : Alice Törne; [2023]
   Keywords : MSC Characterization; Differentiation; Flowcytometry; Culturing media; T24;

   Abstract : The mesenchymal stromal cell (MSC) is of great interest for its immunomodulatory and regenerative properties. However, to research and use these MSCs it is essential to identify and characterize them as such. They need to fulfill the MSCs' minimal criteria which assess the differentiation potential, cell surface markers, and adherence. READ MORE

4. 3. The Role of Endoplasmic Reticulum Stress and Hepatic Stellate Cells in Inducing Chemoresistance in Hepatocellular Carcinoma

   University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

   Author : Jaafar Khaled; [2021]
   Keywords : Hepatocellular carcinoma; ER-stress; hepatic stellate cells; chemoresistance; doxorubicin; 4μ8C; Hepatocellulärt karcinom; ER-stress; hepatiska stellatceller; kemoresistens; doxorubicin; 4μ8C;

   Abstract : Hepatocellular carcinoma (HCC) is the most common liver malignancy that usually develops in patients suffering from chronic liver diseases. One of the major problems faced in the treatment of HCC is severe chemoresistance. READ MORE

5. 4. Subcellular mapping of cell types in healthy human pancreatic islets

   University essay from KTH/Proteinvetenskap

   Author : Frida Björklund; [2021]
   Keywords : Pancreatic islets; Multiplex tissue imaging; CODEX; DNA-conjugated antibodies; Spatial cell biology; Langerhanska öar; Multiplex mikroskopisk avbildning av vävnad; CODEX; DNA-konjugerade antikroppar; Spatial cellbiologi;

   Abstract : Pancreatic islets are composed of endocrine cells that secrete hormones essential for blood-glucose homeostasis. Prior research has revealed that the gene expression and functionality of human islet cells is heterogenous. READ MORE

6. 5. Sex differences in neuronal differentiation of human stem cells

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Olga Doszyn; [2019]
   Keywords : stem cells; neural stem cells; embryonic stem cells; sex differences; neuronal differentiation;

   Abstract : Sexual dimorphism has been long noted in human neurobiology, apparent most notably in sex-biased distribution of multiple neurological disorders or diseases, from autism spectrum disorder to Parkinson's disease. With the advances in molecular biology, genetics and epigenetics have come into focus as key players in sexually dimorphic neural development; and yet, many studies in the field of neuroscience overlook the importance of sex for the human brain. READ MORE