Essays about: "In-vitro differentiation"

Showing result 1 - 5 of 27 essays containing the words In-vitro differentiation.

  1. 1. The effect of calcium silicate-based cements on viability and differentiation of human stem cells from the dental apical papilla. : Future aspects in endodontic regeneration.

    University essay from Umeå universitet/Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM); Umeå universitet/Tandläkarutbildning

    Author : Lahood Abdalla; Bagir Soltani; [2023]
    Keywords : MTA; Biodentine; SCAP; Regenerativ endodonti; endodonti; traumatiserade tänder; tänder; unga tänder;

    Abstract : Introduction: Pulp necrosis in immature permanent teeth stops root development and may lead to higher risk of cervical fractures and a challenging treatment. Regenerative endodontic treatment (RET) aims to continue tooth development and implies the use of calcium silicate-based cements, such as Mineral trioxide aggregate (MTA) and Biodentine to seal the root canal. READ MORE

  3. 2. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model

    University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Author : Emilie Allentoft Schousboe; [2023]
    Keywords : 3D models; imiquimod; Langerhans cells; MUTZ-3 cell line; pro-inflammatory cytokines; psoriasis;

    Abstract : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. READ MORE

  4. 3. Impact of BPA, BPF and Mixture N1 on DNA-Methylation of GRIN2B and NR3C1 during human neuroprogenitor cell differentiation

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Fysiologi och miljötoxikologi

    Author : Franziska Sophie Richter; [2023]
    Keywords : Epigenetics; Endocrine disrupting chemicals; DNA methylation; EDCs; Mixture effects; BPA; BPF; Mixture N1;

    Abstract : Endocrine disrupting chemicals (EDCs) are ubiquitous and their adverse impact on nature, wildlife and humans is extensively researched. We are constantly exposed to EDCs, such as the widespread and extensively researched Bisphenol A, as well as its substitute Bisphenol F, which is coming into wider use, even though it is much less is researched and limited information is available about its endocrine effects. READ MORE

  5. 4. Hypoxia and hematopoietic stem cell control with the substance Adaptaquin : An evaluation of hematopoietic stem cell’s proliferation and differentiation in artificially induced hypoxia

    University essay from Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Author : Jens Christiansen; [2023]
    Keywords : Adaptaquin; Flow cytometry; Hematopoietic stem cells; Hypoxia; Hypoxia inducible factor; Prolyl hydroxylase; Adaptaquin; Flödescytometri; Hematopoetiska stamceller; Hypoxi; Hypoxi inducerande faktor; Prolylhydroxylas;

    Abstract : Hematopoietic stem cells (HSCs) have historically been difficult to maintain ex vivo with many attempts to culture them in vitro by mimicking their natural biological environment. Providing a hypoxic environment is one way to achieve this goal and can be performed by using hypoxia stimulating compounds that inhibits the degradation of HIF1a which plays an important role in regulating hypoxia. READ MORE

  6. 5. Characterisation and Identification of Human Mesenchymal Stromal Cells and the Impact of Different Culturing Media

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

    Author : Sana Said Yahya; [2023]
    Keywords : Culturing media; Fetal bovine serum; Human serum; Cell proliferation; In-vitro differentiation;

    Abstract : Background: Mesenchymal stromal cells (MSCs) are multipotent cells that can differentiate into various cell types and possess immunomodulatory and anti-inflammatory effects, making them interesting candidates for therapeutic applications. MSCs are present in small quantities in tissues like bone marrow and therefore need to be expanded while preserving their essential characteristics. READ MORE