Essays about: "clinical chemistry"

Showing result 1 - 5 of 25 essays containing the words clinical chemistry.

  1. 1. The Synthesis and Development of Potential Small Molecule Splice Modifiers toward a central nervous system (CNS) target for the treatment of a genetic disease

    University essay from KTH/Kemiteknik

    Author : Flore Miomandre; [2023]
    Keywords : organic synthesis; medicinal chemistry; pharmaceutical candidate; small molecule; genetic disease; organisk syntes; läkemedelskemi; läkemedelskandidat; småmolekylär; genetisk sjukdom;

    Abstract : Behandling av sällsynta sjukdomar är en stående utmaning inom läkemedelskemi då mer än 400 miljoner människor lider av 7000 olika sällsynta sjukdomar där få godkända läkemedel finns tillgängliga. Fokus för detta arbete är att syntetisera läkemedelskandidater för en sällsynt och livslång form av epilepsi med frekventa och långvariga anfall. READ MORE

  3. 2. Effects of plant polar lipids on postprandial glycemic regulation in healthy humans

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Yijia Yao; [2022]
    Keywords : plant polar lipid; meal study; clinical study; postprandial glycemic regulation; applied nutrition and food chemistry; Technology and Engineering;

    Abstract : In light of diabetes becoming a global discussion topic, some steps ought to be taken to help reduce the number of individuals suffering from the disease. Keeping good glycemic control through a healthy diet helps prevent diabetes and cardiovascular disease. Plant lipids are increasingly being studied for their postprandial effects on humans. READ MORE

  4. 3. Effects of pharmaceutical excipients on the chemical stability of therapeutic proteins in a parenteral formulation

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

    Author : Emmanuel Gulangayan Deniola; [2022]
    Keywords : Chemical stability; protein degradation; GA-Z; somatropin; pharmaceutical excipients; liquid chromatography; pharmaceutical technology; Chemistry;

    Abstract : Proteins and peptides are widely used for the prevention, management, and cure of various illnesses. This vast therapeutic potential represents a significant portion of the pharmaceutical industry in the form of vaccines, antibodies, enzymes, and other protein-based therapeutics. READ MORE

  5. 4. Simulation of periodic counter-current chromatography purification of monoclonal antibodies with column degradation

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Erik Friberg; [2022]
    Keywords : Counter-current chromatography; PCC; Monoclonal antibodies; Affinity chromatography; Process control; Chemical engineering; Process simulation; Chemistry;

    Abstract : The purification process of monoclonal antibodies (mAbs) for therapeutic drugs is expensive, especially the chromatography step in which the mAbs are separated from other proteins and cells present in the feed. The antibodies are separated from the feed using affinity chromatography, where only the antibodies interact with active sites within the column, whereas the rest passes through the column without stopping. READ MORE

  6. 5. Effects of Elaphostrongylus spp. infection on haematology and blood chemistry – in moose (Alces alces), reindeer (Rangifer tarandus), goat (Capra aegagrus hircus) and sheep (Ovis aries)

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Elin Engerström; [2021]
    Keywords : E. alces; E. rangiferi; elaphostrongylosis; muscleworm; brainworm; small ruminant; eosinophilia; biochemistry; serum chemistry;

    Abstract : The aim with this study was to investigate the effects Elaphostrongylus alces and Elaphostrongylus rangiferi have on haematology and blood chemistry in experimentally infected animals. The nematodes of genus Elaphostrongylus spp. can cause neurologic disease, myositis, verminous pneumonia and increased mortality. READ MORE