Essays about: "läkemedelskandidat"

Found 3 essays containing the word läkemedelskandidat.

  1. 1. The Synthesis and Development of Potential Small Molecule Splice Modifiers toward a central nervous system (CNS) target for the treatment of a genetic disease

    University essay from KTH/Kemiteknik

    Author : Flore Miomandre; [2023]
    Keywords : organic synthesis; medicinal chemistry; pharmaceutical candidate; small molecule; genetic disease; organisk syntes; läkemedelskemi; läkemedelskandidat; småmolekylär; genetisk sjukdom;

    Abstract : Behandling av sällsynta sjukdomar är en stående utmaning inom läkemedelskemi då mer än 400 miljoner människor lider av 7000 olika sällsynta sjukdomar där få godkända läkemedel finns tillgängliga. Fokus för detta arbete är att syntetisera läkemedelskandidater för en sällsynt och livslång form av epilepsi med frekventa och långvariga anfall. READ MORE

  3. 2. Effects of Different Laminins on Human Neural Progenitor Cells Cultured in 3D Electrospun Fibers

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Karl Vesterlund; [2019]
    Keywords : two-dimensional; three-dimensional; Alamar Blue; cell culture; drug development; extra-cellular matrix; electrospinning; immunocytochemistry; laminin; polycaprolactone; polymerase chain reaction; western blot; applied biochemistry; tillämpad biokemi; Technology and Engineering; Biology and Life Sciences;

    Abstract : A low success rate of drug candidates in clinical trials, and especially in brain research, motivates development of better screening models. Hence, in neuroscience and many other fields of Life Science, development of more physiological relevant experimental cell-based models is motivated. READ MORE

  4. 3. Synthesis of the sialic acid 9-C derivative with an amino group replacing the OH-group.

    University essay from Lunds universitet/Kemiska institutionen

    Author : Hanna Malmquist; [2018]
    Keywords : organic chemistry; sialic acids; antibiotics; organic synthesis; organisk kemi; Chemistry;

    Abstract : Almost everyone is aware of the big problem with increasing antibiotic resistance among bacteria and the importance and need of developing new antibiotics. This bachelor thesis is a part of one such project with the aim to find new possible antibiotics. A promising candidate is a derivative of the sialic acids. READ MORE