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Showing result 1 - 5 of 8 essays matching the above criteria.

  1. 1. Investigating the protein-protein Interaction between Aquaporin 4 & Calmodulin

    University essay from Lunds universitet/Kemiska institutionen

    Author : Zahraa Majhool; [2020]
    Keywords : aquaporin4 protein-protein; interaction calmodulin ; biochemistry; molecular biology; biokemi; molekylärbiologi; Chemistry;

    Abstract : Around 60 million people around the world are struggling with a traumatic brain or spinal cord injury. The swelling of the brain or spinal cord happen when the water content in the CNS increase due, infection, tumor growth or brain edema. READ MORE

  2. 2. Do Nanoparticles Affect Neuronal Function? - Establishment of a Microelectrode-Based Assay

    University essay from Lunds universitet/Tillämpad biokemi

    Author : Markus Nylander; [2020]
    Keywords : Microelectrode array; gold nanoparticles; silver nanoparticles; immunocytochemistry; scanning electron microscopy; human neural progenitor cells; human induced pluripotent stem cells; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering;

    Abstract : Nanomaterials are used extensively in industry and daily life but comparatively little is known about the possible health effects. Silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) are two metal nanoparticles that have been intensively studied. READ MORE

  3. 3. CHARACTERIZATION OF EARLY LIFE EXPOSURE TO ENVIRONMENTAL CHEMICALS AND ITS IMPACTS ON HEALTH

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Lisanna Sinisalu; [2020]
    Keywords : ;

    Abstract : The exposome is a complex study that includes both endogenous and exogenous markers related to different diseases as part of the research. Connecting both endogenous and exogenous markers can help explain many associations between environmental chemicals and metabolic profiles, which can be stressors for causing different diseases. READ MORE

  4. 4. Towards the identification of environmental exposures and epigenetic marks related to the etiology of Autism

    University essay from Linköpings universitet/Biologi

    Author : Stefan Miemczyk; [2017]
    Keywords : autism spectrum disorders; cord blood; environmental factors; metals; method optimization; mitochondrial DNA; rheumatoid arthritis;

    Abstract : Autism is a complex disorder with possible genetic, epigenetic and environmental components. As the etiology remains uncertain and an increase in incidence is suspected, the involvement of possible environmental risk factors has gained increasing attention. With this thesis, I aim to provide tools for assessing such risk factors. READ MORE

  5. 5. Towards Identifying Pharmacodynamic Blood Biomarkers of MAP3K12 Inhibition

    University essay from Lunds universitet/Tillämpad biokemi

    Author : Elisabeth Jirström; [2017]
    Keywords : Mitogen-activated protein kinase kinase kinase; MAP3K12; Amyotrophic lateral sclerosis; DLK; ALS; Pharmacodynamic; Biomarker; applied biochemistry; tillämpad biokemi; Technology and Engineering; Biology and Life Sciences; Medicine and Health Sciences; Chemistry;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of upper and lower motor neurons in the brain and spinal cord, for which there is no cure. Activation of the stress-induced c-Jun N-terminal kinase (JNK) signaling pathway, a critical mediator of neuronal apoptosis and axon degeneration, is evident in ALS and is therefore considered a potential target to prevent neurodegeneration. READ MORE