Essays about: "human neural progenitor cells"

Showing result 1 - 5 of 6 essays containing the words human neural progenitor cells.

  1. 1. Impact of BPA, BPF and Mixture N1 on DNA-Methylation of GRIN2B and NR3C1 during human neuroprogenitor cell differentiation

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Fysiologi och miljötoxikologi

    Author : Franziska Sophie Richter; [2023]
    Keywords : Epigenetics; Endocrine disrupting chemicals; DNA methylation; EDCs; Mixture effects; BPA; BPF; Mixture N1;

    Abstract : Endocrine disrupting chemicals (EDCs) are ubiquitous and their adverse impact on nature, wildlife and humans is extensively researched. We are constantly exposed to EDCs, such as the widespread and extensively researched Bisphenol A, as well as its substitute Bisphenol F, which is coming into wider use, even though it is much less is researched and limited information is available about its endocrine effects. READ MORE

  2. 2. Epigenetic and transcriptional effects of full-length LINE-1 retrotransposons in human neural progenitor cells

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Ninoslav Pandiloski; [2021]
    Keywords : Biology and Life Sciences;

    Abstract : Transposable elements (TE) are parasitic genetic entities that have the ability to alter their position within a genome and have the potential to influence its functionality. Although TEs play beneficial roles in the evolution of their host, they are active in various human disorders including neurological diseases, where may contribute to the progress of the disease. READ MORE

  3. 3. Do Nanoparticles Affect Neuronal Function? - Establishment of a Microelectrode-Based Assay

    University essay from Lunds universitet/Tillämpad biokemi

    Author : Markus Nylander; [2020]
    Keywords : Microelectrode array; gold nanoparticles; silver nanoparticles; immunocytochemistry; scanning electron microscopy; human neural progenitor cells; human induced pluripotent stem cells; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering;

    Abstract : Nanomaterials are used extensively in industry and daily life but comparatively little is known about the possible health effects. Silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) are two metal nanoparticles that have been intensively studied. READ MORE

  4. 4. How Topography Influences the Fate of Human Neural Progenitor Cells

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Jacob Karlström; [2020]
    Keywords : biomaterials; cell culture; electrospinning; nanofibers; 3d; neural progenitor cells; in vitro models; nanotopography; blebbistatin; mechanotransduction; nucleus analysis; immunocytochemistry; differentiation; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering;

    Abstract : Novel biomimetic three-dimensional scaffolds have emerged over the last decades, and are promising for applications in regenerative therapies, as well as in in vitro disease modelling and drug testing. Thanks to their added dimension, these scaffolds are able to more accurately mimic the topography of native cellular microenvironments compared to traditionally used two-dimensional culture substrates. READ MORE

  5. 5. Effects of Different Laminins on Human Neural Progenitor Cells Cultured in 3D Electrospun Fibers

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Karl Vesterlund; [2019]
    Keywords : two-dimensional; three-dimensional; Alamar Blue; cell culture; drug development; extra-cellular matrix; electrospinning; immunocytochemistry; laminin; polycaprolactone; polymerase chain reaction; western blot; applied biochemistry; tillämpad biokemi; Technology and Engineering; Biology and Life Sciences;

    Abstract : A low success rate of drug candidates in clinical trials, and especially in brain research, motivates development of better screening models. Hence, in neuroscience and many other fields of Life Science, development of more physiological relevant experimental cell-based models is motivated. READ MORE