Essays about: "eQTLs"

Found 4 essays containing the word eQTLs.

  1. 1. The role of RFX-target genes in neurodevelopmental and psychiatric disorders

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Abhishekapriya Ganesan; [2021]
    Keywords : ;

    Abstract : Neurodevelopmental disorders such as autism spectrum disorder (ASD) and psychiatric disorders, for example, schizophrenia (SCZ) represent a large spectrum of disorders that manifest through cognitive and behavioural problems. ASD and SCZ are both highly heritable, and some phenotypic similarities between ASD and SCZ have sparked an interest in understanding their genetic commonalities. READ MORE

  3. 2. Causality in Coexpression

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Carolina Barros; [2020]
    Keywords : bioinformatics; computational biology; genomics; causality; genetics; coexpression;

    Abstract : One of the main goals of genetics has been to understand the link between genotype and phenotype. Using yeast (Saccharomyces cerevisiae) as our model organism, we take a closer look at the connection between genetic variation and gene expression to learn more about the mechanisms of gene regulation. READ MORE

  4. 3. Systematic comparison of gene regulatory datasets using experimentally validated enhancers

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Xue Dong; [2020]
    Keywords : Capture Hi-C; ChIP-seq; enhancer; promoter-enhancer interactions; eQTLs;

    Abstract : Promoter-enhancer interactions are essential for gene regulating, Capture Hi-C is a chromosome conformation capture method to map promoter-enhancer interactions at high resolution. We have Capture Hi-C data forGM12878 cells, immortalized primary B lymphocytes, in three replicates. READ MORE

  5. 4. Analysis of the expression of INSR and FOX Genes in Celiac Disease

    University essay from Institutionen för vård och natur

    Author : Daniel Yemane Hagos; [2012]
    Keywords : Celiac disease; reverse transcription; target genes; reference genes; QPCR; Relative quantification; Fold change.;

    Abstract : Celiac disease (CD) is a common heritable immune related disorder where chronic inflammationof the small intestine is induced by the ingestion of gluten. The immune response leads to theinflammation and flattening of intestinal mucosa due to the damaged villi and thus results indefects in the absorption of nutrients. READ MORE