Essays about: "histone modification"
Found 5 essays containing the words histone modification.
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1. Cancer Driver Gene Detection using Deep Convolutional Neural Networks on H3K4me3 Enrichment Profiles
University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisationAbstract : In spite of our current knowledge regarding the biology underlying cancer genesis, reliable methods for the discovery of cancer driver (CD) genes are still in great need. The rather recent incorporation of epigenetic markers to the cancer paradigm has nevertheless opened the door for the development of new computational approaches to the problem. READ MORE
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2. Targeting the epigenetic state of refractory and relapsing acute myeloid leukaemia
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Acute myeloid leukaemia (AML) is a heterogeneous group of myeloid lineage malignancies arising from a spectrum of mutations. AML is characterized by the uncontrolled proliferation of clonal cells, which are unable to properly differentiate into mature myeloid cells. READ MORE
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3. Histone modifications and their role in splicing
University essay from Linköpings universitet/BiologiAbstract : Splicing is the process when introns gets removed and exons are spliced together. This is an important step to form a clean mRNA with no unnecessary sequences that could interrupt protein synthesis. There are different types of splicing and some of them need a complex called spliceosome. READ MORE
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4. Epigenetiskt arv
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : Epigenetik är den del av genetiken som behandlar förändringar i genuttryck som är oberoende av förändringar i DNA-sekvensen. Det som styr vilka gener som uttrycks och får effekt på fenotyp har studerats av forskare sedan 70-80-talet. READ MORE
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5. Histone modifications after DNA damage affect survival in Schizosaccharomyces pombe
University essay from Institutionen för livsvetenskaperAbstract : S. cerevisiae Ada2 and Bre1 has a role in histone post-translational modifications. Deletion of these genes causes deficiency in acetylation (Ada2) or ubiquitination (Bre1) of histones. Further, mutants lacking these genes or homologous genes showed different phenotypes in human and S. READ MORE