Essays about: "hybridoma"

Found 2 essays containing the word hybridoma.

  1. 1. Soft sensor application on lactate controlled fed-batch cultivation for monoclonal antibody production

    University essay from Linköpings universitet/Teknisk biologi; Linköpings universitet/Tekniska högskolan

    Author : Karlberg Micael; [2015]
    Keywords : ;

    Abstract : Monoclonal antibody producing cells are of great interest and used frequently in the field of biomedical research, diagnostics and therapy with increasing need for better systems to more efficiently produce antibodies at a lower costs. In this project three fed-batch cultivations of hybridoma cells (HB-8696) were cultured in a stirred tank reactor with the use of a soft sensor to monitor the lactate concentration and as well as a dielectric probe for biomass measurements. READ MORE

  2. 2. Evaluation of on-line cell viability and L-lactate measurements in soft sensor for mammalian cell cultures

    University essay from Linköpings universitet/Teknisk biologi; Linköpings universitet/Tekniska högskolan

    Author : Alexander Reissig; [2014]
    Keywords : hybridoma; B lymphocytes; batch reactor; soft sensor; lactate; L-lactate; radio-frequency impedance; BioSenz; enzyme thermistor; overflow metabolism;

    Abstract : Increasing demand on more effective cell culture reactors has driven optimization works to increase output of products. This has led to development of soft sensors that uses mathematical formulas to increase the available information for the parameters during runs. READ MORE