Essays about: "signal amplification"

Showing result 1 - 5 of 44 essays containing the words signal amplification.

  1. 1. Development of ultra-sensitive immunoassay on Gyrolab microfluidic platform using Binding Oligo Ladder Detection : Enhancing Gyrolab biomarker assays using Exazym®

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Sam Vadi Dris; [2024]
    Keywords : Immnoassay; Gyrolab; TNF-alpha; Ultra-sensitive; Cavidi; Exazym; BOLD amplification; Amplification;

    Abstract : Immunoassays are widely used for detection of antigens in a wide range of applications including assays in pharmaceutical development. Immunoassays are continuously improved in many aspects including automatization, miniaturization and extending the dynamic range. READ MORE

  3. 2. Comparison and optimization of extracellular vesicle (EV) capturing on functional thin films for their molecular profiling

    University essay from KTH/Tillämpad fysik

    Author : Prattakorn Metem; [2023]
    Keywords : extracellular vesicle; plasmonic nanohole array; atomic force microscopy; fluorescence analysis; extracellulära vesiklar; nanohålsuppsättning; atomkraftsmikroskopi; fluorescensanalys;

    Abstract : Extracellular vesicles (EVs) are lipid bilayer encapsulated nanoparticles which have emerged as an excellent source of biomarkers for multiple diseases, including cancer. However, they are highly heterogeneous in their molecular compositions which remains a major challenge hindering the utilization of their biomarker potential. READ MORE

  4. 3. Signal amplification in a microfluidic immunoassay system via Binding Oligo Ladder Detection : Applying the Exazym® signal amplification to the Gyrolab® platform

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Daniel Wiman; [2023]
    Keywords : immunoassay; ultra-sensitive; signal amplification; Gyrolab; Exazym; high sensitivity; microfluidics; BOLD amplification; nucleic acid polymerisation;

    Abstract : Immunoassays are analytical methods that use the highly specific binding of antibodies in order to detect and quantify an analyte. The technique has become a staple in modern biopharmaceutical research and diagnostics, however the measurement of biomarkers like dysregulated cytokines require ultra-sensitive immunoassays that can detect molecules at sub pg/mL concentrations. READ MORE

  5. 4. Design and Fabrication of a Kinetic Inductance Parameric Amplifier for multi-mode entanglement studies

    University essay from KTH/Tillämpad fysik

    Author : Sara Persia; [2022]
    Keywords : Parametric amplifier; kinetic inductance; superconducting NbTiN nanowires; Parametrisk förstärkare; kinetisk induktans; supraledanden NbTiN- nanotrådar;

    Abstract : Parametric amplifiers are essential for analyzing and measuring the weak signals generated byquantum circuits at cryogenic temperatures. This project aims to realize a low noise travelingwave parametric amplifier (TWPA) by exploiting the nonlinear current dependence of thekinetic inductance of superconducting NbTiN nanowires. READ MORE

  6. 5. Gas in Scattering Media Absorption Spectroscopy in Large Geometries: Towards Monitoring Oxygen in Adult Lungs

    University essay from Lunds universitet/Förbränningsfysik; Lunds universitet/Fysiska institutionen

    Author : Anna Brandt; [2022]
    Keywords : Physics and Astronomy;

    Abstract : GAs in Scattering Media Absorption Spectroscopy (GASMAS) is a technique to study free gas inside strongly scattering bulk-materials. GASMAS is successful in safely measuring oxygen in lungs of neonates, with low-power tuneable diode-laser spectroscopy at 760 nm. READ MORE