Essays about: "Bioinformatics"

Showing result 11 - 15 of 181 essays containing the word Bioinformatics.

1. 11. SubKluster: Novel method to bin scaffolds from cereal genomes into subgenomes using substring frequency analysis

   University essay from Lunds universitet/Examensarbeten i bioinformatik

   Author : Victor Kalbskopf; [2023]
   Keywords : Biology and Life Sciences;

   Abstract : The genome of the Belinda variety of the hexaploid oat (Avena sativa) has recently been sequenced and assembled. This project aims to improve the assembly by clustering the thousands of scaffolds into their three ancestral subgenomes using Principle Component Analysis (PCA) of kmer and repeat-element frequencies. READ MORE

3. 12. CRISPR-Drawr, a tool to design mutagenic primer

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Larsson Torbjörn; [2023]
   Keywords : Integrated CRISPR design; new score method; short open reading frames; functional screening; bioinformatics;

   Abstract : Short open reading frames (sORFs) are codon sequences with a start and stop codon within atmost 100 codons. Cells produce many transcripts from them and some sORFs have been found to have function. sORFs have been associated with embryogenesis, myogenesis, immunity and various diseases including cancers. READ MORE

4. 13. Exploring the genetic cause of myotonic dystrophy in horses

   University essay from SLU/Dept. of Animal Breeding and Genetics

   Author : Thomas Simon; [2023]
   Keywords : genetics; bioinformatics; myotonic dystrophy; horses; variant analysis;

   Abstract : Myotonic Dystrophy (MD) is an inherited neuromuscular disorder that leads to a wide range of clinical signs including stiffness, abnormal muscle relaxation, and muscle atrophy or hypertrophy. Affected muscles develop a prolonged contracture in response to percussion of the muscle and show waxing and waning complex repetitive discharges in electromyography (EMG). READ MORE

5. 14. Predicting morphological effect of compounds on COVID-19 infected cells

   University essay from Uppsala universitet/Läkemedelsdesign och läkemedelsutveckling

   Author : Viktor Öhrner; [2023]
   Keywords : QSAR; ML; AI; bioinformatics; COVID-19; morphological profiles;

   Abstract : The cost of developing new drugs is high and the aim of computer-assisted drug discovery is to reduce that development cost, either through virtual screening or generating novel compounds. System biology is one approach to drug discovery where the response of a biological system is the subject of study, instead of drug target interaction. READ MORE

6. 15. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

   University essay from Lunds universitet/Examensarbeten i bioinformatik

   Author : Yi Su; [2023]
   Keywords : Biology and Life Sciences;

   Abstract : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. READ MORE