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Showing result 1 - 5 of 31 essays matching the above criteria.

  1. 1. Methodological development of human telomere sequencing with the Oxford Nanopore Technologies

    University essay from Örebro universitet/Institutionen för hälsovetenskaper

    Author : Jennifer Arnqvist; [2023]
    Keywords : ;

    Abstract : Human DNA is protected with telomeres, which consist of the repetitive DNA-sequence TTAGGG. A 3’-overhang folds back and in combination with the shelterin complex protects the ends of the DNA. READ MORE

  3. 2. Platelet function after storage in leukocyte : reduced whole blood and preheating to 37°C

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Alma Bolmsvik; Sofia Bjelkvik; [2023]
    Keywords : Blood platelets; blood transfusion; flow cytometry; blood cell count; platelet membrane glycoproteins; platelet activation.;

    Abstract : Introduction: Whole blood transfusions are indicated for the resuscitation of patients with hemorrhagic trauma. In Sweden, whole blood is stored for 14 days at 4°C. If possible, refrigerated blood is rewarmed to 37°C before transfusion to avoid hypothermia. Platelets contribute to hemostasis and can be activated with several pathways. READ MORE

  4. 3. Priorities in Pairwise Kidney Exchanges - A Simulation Study on European Kidney Exchange Programs

    University essay from Lunds universitet/Läkarutbildningen

    Author : Samuel Lundgren; [2023]
    Keywords : Kidney Exchange; Pairwise Kidney Exchange; KEP; Priority; ESRD; Kidney Transplantation; Mathematics and Statistics; Medicine and Health Sciences;

    Abstract : Background: For most patients with end stage renal disease (ESRD) kidney transplantation is the best treatment option. Best outcomes are achieved with living donation. To increase access to living donation for patients who are not compatible with their living donors, Kidney Exchange Programs (KEPs) have evolved. READ MORE

  5. 4. Evaluation of the platelet yield index on interim platelet units from Reveos by comparison with platelet count from Sysmex

    University essay from

    Author : Jennifer Ahlin; [2023]
    Keywords : fluorescent flow cytometry; transfusion; blood component; automation; blood processing system;

    Abstract : Background: Platelets are the smallest cells in the blood and are involved in the wound healing process. Platelet transfusion is an important part of treating illnesses such as thrombocytopenia and to prevent and stop major bleedings. READ MORE

  6. 5. Identification of Immunological Targets for Brain Cancer Immunotherapy

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Zhenda Wang; [2022]
    Keywords : Cancer immunotherapy; brain cancer; neoantigen; MHC HLA; TCR;

    Abstract : Background Cancer immunotherapy has yielded many successes. Yet to some hard-to-treat brain tumors, such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), it still lacks substantial improvement. Neoantigens resulting from mutations in malignant cells are the key targets for employing adoptive cell therapies. READ MORE