Essays about: "platelet activation."

Showing result 1 - 5 of 15 essays containing the words platelet activation..

  1. 1. Platelet function after storage in leukocyte : reduced whole blood and preheating to 37°C

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Alma Bolmsvik; Sofia Bjelkvik; [2023]
    Keywords : Blood platelets; blood transfusion; flow cytometry; blood cell count; platelet membrane glycoproteins; platelet activation.;

    Abstract : Introduction: Whole blood transfusions are indicated for the resuscitation of patients with hemorrhagic trauma. In Sweden, whole blood is stored for 14 days at 4°C. If possible, refrigerated blood is rewarmed to 37°C before transfusion to avoid hypothermia. Platelets contribute to hemostasis and can be activated with several pathways. READ MORE

  3. 2. Ligand-stimulated cleavage of PDGFR-beta

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Agni Karolina Tsiatsiou; [2023]
    Keywords : ;

    Abstract : Platelet-derived growth factor receptors (α and β) are included in the family of receptor tyrosine kinases (RTKs). The dimeric PDGF ligands bind to the PDGF receptors and this results in receptor dimerization, autophosphorylation, and thus activation. The autophosphorylated receptor dimer activates numerous signaling pathways. READ MORE

  4. 3. Blood interactions with bioactive peptidefunctionalized nanocellulose : An evaluation of the activation of the coagulation and complement system

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Vanisha Bansal; [2022]
    Keywords : ;

    Abstract : A current trend utilizing the biomedical approach in the field of wound care is focused on the increased potential to develop wound healing materials designed to address specific types of wounds or underlying pathologies to achieve improved healing. The work presented in this thesis evaluates the blood response to wood-derived nanocellulose functionalized with a peptide, with the ultimate aim of characterizing the material as a potential wound dressing for chronic wound care. READ MORE

  5. 4. The role of Platelet-derived growth factor receptor β-signaling in non-small cell lung cancer

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Author : Louise Hellberg; [2022]
    Keywords : pathology; lung cancer; PLA; PDGFR;

    Abstract : A high expression of stromal PDGFRβ is known to be a poor prognosis marker in several solid tumor types. However, the role of stromal PDGFRβ for non-small cell lung cancer (NSCLC) patients remains unclear. READ MORE

  6. 5. Molecular mechanisms underlying platelet inhibition obtained by novel piperazine-purine analogues

    University essay from Örebro universitet/Institutionen för medicinska vetenskaper

    Author : Josef Jakobsson; [2021]
    Keywords : ;

    Abstract : Introduction. MK-substances are a new class of piperazine-purine analogues bearing nitrate esters with confirmed cardioprotective, anti-inflammatory and antithrombotic effects. READ MORE