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Showing result 1 - 5 of 10 essays matching the above criteria.

  1. 1. Virtual H&E Staining Using PLS Microscopy and Neural Networks

    University essay from Lunds universitet/Matematik LTH

    Author : Sally Vizins; Hanna Råhnängen; [2024]
    Keywords : Deep learning; Virtual staining; Skin tissue; Hematoxylin Eosin; H E; Pathology; Carcinoma; Point light source illumination; Neural Networks; GANs; Generative adversarial networks; CNNs; Convolutional neural networks; Relativistic generative adversarial network; Unet; Digital microscopy; Attention-Unet; Dense-Unet; Mathematics and Statistics;

    Abstract : Histopathological examination, crucial in diagnosing diseases such as cancer, traditionally relies on time- and resource-consuming, poorly standardized chemical staining for tissue visualization. This thesis presents a novel digital alternative using generative neural networks and a point light source (PLS) microscope to transform unstained skin tissue images into their stained counterparts. READ MORE

  2. 2. Using Generative Adversarial Networks for H&E-to-HER2 Stain Translation in Digital Pathology Images

    University essay from Linköpings universitet/Institutionen för medicinsk teknik

    Author : William Tirmén; [2023]
    Keywords : Machine learning; Artificial intelligence; Digital pathology; Image processing; Generative adversarial networks; Image-to-image translation;

    Abstract : In digital pathology, hematoxylin & eosin (H&E) is a routine stain which is performed on most clinical cases and it often provides clinicians with sufficient information for diagnosis. However, when making decisions on how to guide breast cancer treatment, immunohistochemical staining of human epidermal growth factor 2 (HER2 staining) is also needed. READ MORE

  3. 3. The Effect of Angiogenesis Inhibition on Tumor-Associated Granulocytes in an Orthotopic Model of High-Risk Neuroblastoma

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Maja Hammarström; [2022]
    Keywords : neuroblastoma; tumor angiogenesis; sunitinib; SU11248; tumor-associated neutrophils; immunohistochemistry;

    Abstract : Background: Neuroblastoma is the most common extracranial solid tumor in children. The survival rate in high-risk neuroblastoma is less than 50 % despite intensive multimodal therapy, and there is thus an immense need for new treatment options. READ MORE

  4. 4. Determining the Acoustic Mobility of Breast Cancer Cells

    University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

    Author : Simon Olsson; [2022]
    Keywords : Technology and Engineering;

    Abstract : Breast cancer is one of the most common forms of cancer detected in women. Its heterogeneity and large mutational landscape requires treatment strategies which varies between patients. Triple negative breast cancer (TNBC) is a particularly aggressive subtype which 12-17 \% of breast cancer patient develop. READ MORE

  5. 5. Differences in aluminum tolerance of populus genotypes : development of methodology for identification of poplar genotypes suitable for acidic forest land

    University essay from SLU/Southern Swedish Forest Research Centre

    Author : Mikas Arlauskas; [2020]
    Keywords : populus; poplar; poplar hybrids; aluminum; aluminum tolerance; aluminum sensitivity; aluminum susceptibility; aluminum toxicity;

    Abstract : Forest lands hold great potential for Populus plantations for bionenergy purposes. However in native boreal forests where land for establishing these plantations is abundant poplars encounter challenges in establishment. READ MORE