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Showing result 1 - 5 of 41 essays matching the above criteria.

  1. 1. Skillnader mellan granindivider gällande initieringsfrekvens för somatisk embryogenes

    University essay from SLU/School for Forest Management

    Author : Josefine Björs; Jonathan Sjögren; [2023]
    Keywords : skogsträdsförädling; Picea abies; fröklonförökning;

    Abstract : Gran (Picea abies) har länge varit ett viktigt trädslag för den svenska skogsnäringen. Skogsbruket står inför en oviss framtid och med ett alltmer ostadigt klimat behövs ett genetiskt material som kan klara dessa nya prövningar. READ MORE

  3. 2. Molecular characterization of vascular malformations using single-cell RNA sequencing and immunohistological analysis

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Amanda Norrén; [2023]
    Keywords : ;

    Abstract : CCM is a human disease in which vascular malformations develop in the central nervous system, predominantly in the brain. The malformations which can measure up to several centimeters in size are dilated and leaky vessels, with unstable cellular junctions and thin vessel walls. READ MORE

  4. 3. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse

    University essay from KTH/Proteinvetenskap

    Author : Intisar Salim; [2023]
    Keywords : Huntington’s Disease; mRNA-seq; tissue specific gene expression; cerebrospinal fluid; biomarker; Huntingtons sjukdom; mRNA-seq; vävnadsspecifik genexpression; cerebrospinalvätska; biomarkör;

    Abstract : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. READ MORE

  5. 4. Molecular mapping of the HGSOC tumour microenvironment

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Philippine Louail; [2023]
    Keywords : Immunology; Ovarian cancer; Multiplex Immunofluorescence; scRNA sequencing; Bioinformatics; Image analysis;

    Abstract : High-grade serous ovarian cancer (HGSOC) is the most aggressive subtype of ovarian cancer, and its heterogeneity poses a challenge for the discovery of reliable diagnostic biomarkers, therapeutic targets, and predicting treatment response, particularly to immunotherapy. The current standard diagnostic and treatment options are inadequate, resulting in late diagnosis and poor prognosis. READ MORE

  6. 5. Identifying molecular markers for breeding a future oil crop, Lepidium campestre

    University essay from SLU/Dept. of Plant Breeding (from 130101)

    Author : Noomi Lodenius; [2023]
    Keywords : glucosinolate content; interspecific hybridization; Lepidium campestre; marker discovery; oil content; oil quality;

    Abstract : The cold hardy novel oil- and cover crop Lepidium campestre is currently being domesticated as a potential oil crop for the Nordic region. To achieve this objective, multiple traits have previously been identified as desirable to improve, including seed oil content and composition, and glucosinolate (GL) content. READ MORE