Essays about: "Protein conformation"

Showing result 6 - 10 of 32 essays containing the words Protein conformation.

  1. 6. Evaluating a coarse-grained IDP-model for structure and dynamics

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Louise Kalander; [2021]
    Keywords : IDP; Intrinsically disordered proteins; Histatin 5; Simulation; Biophysical chemistry; Chemistry;

    Abstract : In this study a coarse-grained model of intrinsically disordered proteins (IDPs) is evaluated to determine whether the model is suitable to use for analyzing the structure and dynamics of IDPs. IDPs are proteins that lack a stable tertiary structure which gives them a flexible structure. READ MORE

  3. 7. Characterization of Alcohol Modulation of a Pentameric Ligand-gated Ion Channel with Electrophysiology and Molecular Dynamics Simulations

    University essay from KTH/Tillämpad fysik

    Author : Sabina Gutheim; [2021]
    Keywords : Biophysics; Electrophysiology; MD simulations; Ligand-gated ion channels; GLIC; Ethanol modulation; Biofysik; Elektrofysiologi; MDsimuleringar; Pentameriska ligandstyrda jonkanaler; GLIC; Etanolmodulering;

    Abstract : Pentameric ligand-gated ion channels (pLGICs) are membrane receptors that play a crucial role in every living organism. The pLGIC protein structure forms a pore through the membrane of a cell that can let specific ions pass through, upon activation by endogenous agonists. READ MORE

  4. 8. Structural basis of modulation by pH and calcium in a ligand-gated ion channel

    University essay from KTH/Genteknologi

    Author : Olivia Andén; [2021]
    Keywords : Pentameric ligand-gated ion channels; bacterial homolog; protein expression; protein purification; cryo-electron microscopy; data processing; protein structure; Pentamerisk ligandstyrd jonkanal; bakteriell homolog; proteinexpression; proteinrening; kryo-elektronmikroskopi;

    Abstract : Pentameriska ligandstyrda jonkanaler (pLGICs) är avgörande för omvandlingen av kemisk till elektrisk signalöverföring i djurs nervsystem. Dysfunktion i dessa kanaler har visat sig vara kopplad till flera sjukdomar inklusive epilepsi, schizofreni, Alzheimers och autism, vilket gör dem till en måltavla för en mängd olika läkemedel. READ MORE

  5. 9. Exploring connectivity patterns in cancer proteins with machine learning

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Knut-Rasmus Bergendal; [2021]
    Keywords : Self-Organizing map; machine learning; Protein conformation; Cancer mutations; självorganiserande karta; maskininlärning; Proteinstruktur; Cancermutationer;

    Abstract : Proteins are among the most versatile organic macromolecules essential for living systems and present in almost all biological processes. Cancer is associated with mutations that either enhance or disrupt the conformation of proteins. These mutations have been shown to accumulate in specific regions of a proteins three dimensional structure. READ MORE

  6. 10. Korrelation av kliniska och genetiska data hos älgar diagnosticerade med och utan Moose Wasting Syndrome

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Rosie Johannesson; [2020]
    Keywords : älg; Moose Wasting Syndrome; undernäring; sjukdomsdata;

    Abstract : År 1985 upptäcktes en sjukdom som drabbade svenska älgar. Sjukdomen fick namnet Moose Wasting Syndrome (MWS). Älgarna som hittades var i mycket dålig kondition eller självdöda. Symptomen på MWS är anorexi, svaghet, nedsatt syn, minskad skygghet, utmärgling och diarré. READ MORE