Essays about: "long non-coding RNA"
Showing result 1 - 5 of 12 essays containing the words long non-coding RNA.
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1. Non-coding RNAs as therapeutic agents : The future of therapy
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. READ MORE
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2. Comprehensive Analysis of lncRNA and circRNA Mediated ceRNA network in Psoriasis
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Evidence is accumulating that noncoding RNAs and circRNA are involved in psoriasis; however, the competing endogenous RNA (ceRNA) mediated regulatory mechanisms in psoriasis are rarely reported. The research study aimed to comprehensively investigate the differences in the expression levels of circular RNA (circRNA), long non-coding RNA (lncRNA), microRNA (miRNA/miR), and mRNA in psoriasis. READ MORE
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3. Extraction of miR-223 from human blood plasma and quantification using the two-tailed RT-qPCR and absolute quantification
University essay from Högskolan i Skövde/Institutionen för biovetenskapAbstract : Sepsis is a very dangerous and life-threatening disease that develops when the body’s reaction to infection causes damage to the body’s tissues and organs. It is difficult to diagnose it and it develops fast leading to a high mortality rate. READ MORE
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4. Investigation of the gene expression landscape of human skin wounds
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Wound healing is a complex physiological process. Effective wound healing enables the skin barrier function to be restored once the skin is injured. However, due to the complex nature of wounds, the mechanisms underlying tissue repair are still poorly understood. READ MORE
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5. Regulation of TGFß signalling by the long noncoding RNA TGFß2-AS1
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Long noncoding RNAs have been shown to regulate many signalling pathways and their expression has been linked to the development of many cancers. Here we assess the involvement of the long noncoding RNA TGFß2-AS1 in the regulation of the TGFß signalling pathway, specifically its involvement in the TGFß induced process of EMT. READ MORE
