Essays about: "mitogen-activated protein kinase MAPK"

Showing result 1 - 5 of 6 essays containing the words mitogen-activated protein kinase MAPK.

  1. 1. Characterization of pERK expression in amygdala and its role in nociceptive behavior

    University essay from SLU/Dept. of Microbiology

    Author : Mychelly Moraes De Siqueira; [2016]
    Keywords : amygdala; extracellular signal-regulated kinase ERK ; mitogen-activated protein kinase MAPK ; nociceptive; pain;

    Abstract : Extracellular signal-regulated kinase (ERK), is a member of the mitogen-activated protein kinase (MAPK) family of serine/threonine protein kinases. Functioning as intracellular signaling molecules, they are responsible for multiple extracellular signals transduction into diverse intracellular responses through transcriptional and post-translational regulations. READ MORE

  2. 2. Role of MKP-2 in crosstalk between MAPK pathways

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Ludwiginstitutet för cancerforskning

    Author : Mikaela Åhlin; [2015]
    Keywords : ;

    Abstract : Abnormalities in Mitogen Activated Protein Kinase (MAPK) signalling may affect the cells essential processes and influence the cell in acquiring traits to favour tumorigenic transformation and the progression of cancer. Deregulation of the MAPK pathways and uncontrolled crosstalk occurring in cancers may be caused by deregulation by MAP-kinase phosphatases (MKPs) that negatively regulates MAPKs by dephosphorylation. READ MORE

  3. 3. Heme degradation pathway controls inflammation in model of mouse prostatitis

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Lisa Vikström; [2015]
    Keywords : Biology and Life Sciences;

    Abstract : Acute or chronic inflammation in the prostate is implicated in pathogenesis of benign prostate hyperplasia (BPH) as well as development of prostatic intraepithelial neoplasia (PIN) and prostate cancer (PCa). Chronic prostatitis (inflammation in the prostate) is associated with high morbidity and negatively impacts life quality. READ MORE

  4. 4. Knockdown of the ERK pathway using siRNA in cultured chicken cardiomyocytes

    University essay from Biologi; Tekniska högskolan

    Author : Caroline Ovrén; [2014]
    Keywords : cell culture; RNA interference; cardiomyocytes; ERK; MAPK;

    Abstract : The ancient South American birds called tinamous (Tinamidae) have the smallest hearts known among birds and their cardiomyocytes have previously been shown to express significantly lower levels of the mitogen-activated protein kinase ERK compared to the more modern chicken (Gallus gallus). ERK is a well-known mediator of growth signalling in the heart, especially in hypertrophy. READ MORE

  5. 5. Analysis of Map3k-dependent molecular mechanisms regulating signaling in iNKT and B cells

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Saba Anwar; [2013]
    Keywords : Biology and Life Sciences;

    Abstract : Abstract Our immune system consists of two types of lymphocytes; B lymphocytes which produce antibodies in response to an antigen, and T lymphocytes which differentiate into particular effector T lymphocytes such as a cytotoxic, helper or regulatory T cell in response to an antigen. Type 1 invariant natural killer T cells (iNKT cells) are a unique population of T cells whose phenotypical, developmental and functional characteristics differ from conventional T cells (Novak and Lehuen, 2011). READ MORE