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Found 2 essays matching the above criteria.

1. 1. Investigation of endogenous p21 expression and its correlation to therapy resistance in high-risk neuroblastoma

   University essay from KTH/Proteinvetenskap

   Author : Agnes Sorteberg; [2021]
   Keywords : p21; high-risk neuroblastoma; small molecular inhibitor; chemo-resistance; combination treatment;

   Abstract : Neuroblastoma (NB) is a childhood cancer with a highly complex nature. High-risk NB patients undergo intensive treatment regimens that are often followed by long-term side effects. This, in addition to the emergence of resistant cancer cells, highlights a need for novel therapeutic targets and treatment strategies to improve outcome in NB. READ MORE

3. 2. Mapping the Expression of Cyclin Dependent Kinase Inhibitors in High-Risk Neuroblastoma Cell Lines : Dynamics on Cell-Fate Decisions on Proliferation/Cell Cycle Arrest

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Ximena López Lorenzo; [2020]
   Keywords : Neuroblastoma; NMYC; p53; cell cycle checkpoint; inhibition; regrowth; p21; p27; SKP2; CHK1 2; Neuroblastoma; NMYC; p53; cellcykel checkpoint; hämning; återväxt; p21; p27; SKP2; CHK1 2;

   Abstract : Poor prognosis for high-risk neuroblastoma patients makes it necessary to find novel treatmentstrategies. This work aims to understand the cell cycle behavior of various high-riskneuroblastoma cell lines following chemotherapy treatment. READ MORE