Essays about: "pharmaceutical formulation"

Showing result 1 - 5 of 40 essays containing the words pharmaceutical formulation.

1. 1. Effect of mixing time and mixing rate on the evolution of powderproperties for binary adhesive mixtures

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Noveen Muslih Sadullah; [2024]
   Keywords : Adhesive mixture; mixing time; mixing rate; Budesonide; Lactopress SD;

   Abstract : Dry powder inhalers (DPIs) are often used to deliver drugs to the lungs when treating respiratory diseases. Inhalation powders are often formulated as adhesive mixtures which is the main formulation type used for dry inhalation powders of pharmaceuticals. READ MORE

3. 2. Formulation development, rheological characterization, and cosmetic evaluation of gel-creams

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

   Author : Carl Pontén; [2024]
   Keywords : Rheology; Texture analysis; Viscometry; Semisolids; Design of Experiments; Critical Process Parameters; Critical Quality Atttibutes; Pharmaceutical Technology; Technology and Engineering;

   Abstract : Oil in water (o/w) emulsions are thermodynamically unstable systems composed of small oil droplets dispersed in a continuous aqueous phase. This means that given enough time, the two phases will separate. Pharmaceutical emulsions are used as a method of administering the Active Pharmaceutical Ingredient (API) for topical applications. READ MORE

4. 3. Exploring alternative surfactants to replace PEG within lipid nanoparticles

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)

   Author : Elina Edidovica; [2024]
   Keywords : Lipid nanoparticle; polyethelyne glycol PEG ; alpha-tomatine; N-hexadecyl beta d-maltoside HDM ; DOPC; DPPC; cholesterol; film hydration; stability study; DLS; Cryo-TEM; SAXS; pharmaceutical formulation; Chemistry;

   Abstract : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. READ MORE

5. 4. Effects of mixed surfactant system on chemical and physical stability of human growth hormone

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

   Author : Karnsinee Viriyayudhakorn; [2023]
   Keywords : human growth hormone; surfactant; refolding; protein stability; physical degradation; chemical degradation; pharmaceutical technology; Technology and Engineering;

   Abstract : In protein formulation, addition of surfactants is commonly executed to enhance product stability and shelf-life. The reason is that surfactants can protect proteins against surface-induced aggregation. However, the interaction between surfactant and protein depends on the type of surfactant used. READ MORE

6. 5. Understanding the effects of TCP-25 and EDTA interaction : A study of the biophysical aspects of a naturally derived peptide formulation with EDTA for topical application

   University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)

   Author : Ebba Kant; [2023]
   Keywords : chronic wounds; EDTA; biophysical aspects; formulation; pharmaceutical technology; Thrombin derived C-terminal peptide; Technology and Engineering;

   Abstract : Chronic wounds are an emerging healthcare issue and current methods of healing chronic wounds address bacteria but are ineffective against resistant bacteria and the biofilm formation commonly observed in these wounds. Antimicrobial peptides (AMPs) derived from the endogenous wound healing system have been shown to combat bacterial infections, exhibit immunomodulatory effects, as well as improving wound healing. READ MORE