Essays about: "Lipid nanoparticle"

Showing result 1 - 5 of 7 essays containing the words Lipid nanoparticle.

  1. 1. Exploring alternative surfactants to replace PEG within lipid nanoparticles

    University essay from Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)

    Author : Elina Edidovica; [2024]
    Keywords : Lipid nanoparticle; polyethelyne glycol PEG ; alpha-tomatine; N-hexadecyl beta d-maltoside HDM ; DOPC; DPPC; cholesterol; film hydration; stability study; DLS; Cryo-TEM; SAXS; pharmaceutical formulation; Chemistry;

    Abstract : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. READ MORE

  3. 2. Affibody phage display selections for lipid nanoparticle and affibody-mediated transient CAR T-cell therapy

    University essay from KTH/Proteinvetenskap

    Author : Tasnim Yasin Idris; [2022]
    Keywords : affibody; phage display; in vitro selection; CD5; CD8; CD19; CAR T-cell therapy.;

    Abstract : CAR T-cellbehandling är en immunterapi som har visat lovande resultat vid behandling av cancer. Trots det riktade immunsvaret som kan uppnås, betonar komplexiteten i tillverkningsprocessen och behandlingsproceduren det utrymme somm finns för förbättringar. READ MORE

  4. 3. Nanoparticle-supported lipid bilayers : A novel approach to introduce curvature in model membranes

    University essay from Umeå universitet/Institutionen för integrativ medicinsk biologi (IMB)

    Author : Wourood Hussein; [2021]
    Keywords : ;

    Abstract : .... READ MORE

  5. 4. Exosomes and lipid nanoparticles - the future of targeted drug delivery

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Sara Lundberg; Emelia Karlsson; Hugo Dahlberg; Mathilda Glansk; Sara Larsson; Sofia Larsson; Karl Carlsson; [2020]
    Keywords : Exosomes; lipid nanoparticles; drug delivery;

    Abstract : In this project an overview of how synthetic lipid nanoparticles and exosomes can be used for targeted drug delivery is compiled. The goal is to identify aspects that can be in favor for targeted drug delivery and the development of products at Cytiva. READ MORE

  6. 5. Prominent variable detection in lipid nanoparticle experiments : A simulation study on non-parametric change point analysis

    University essay from Uppsala universitet/Statistiska institutionen

    Author : Hongru Zhai; [2020]
    Keywords : ;

    Abstract : Images as important sources of information, powered by the newest robotic microscopy technologies, make the volume of data available larger than ever before. From the images, hundreds of variables can be calculated. READ MORE