Essays about: "phosphorylation"

Showing result 1 - 5 of 33 essays containing the word phosphorylation.

  1. 1. The role of salt inducible kinases in the regulation of the mammalian target of rapamycin pathway in adipocytes

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Sulochana Kotresh Jali; [2020]
    Keywords : Biology and Life Sciences;

    Abstract : Salt inducible kinase 2 (SIK2) is found abundantly in adipose tissue and may have a role in the development of diabetes. SIK2 is downregulated in insulin-resistant and obese individuals, thereby providing a new potential target for therapeutic solutions. READ MORE

  2. 2. Epigenetic Regulation of Mitochondrial DNA

    University essay from Linköpings universitet/Institutionen för fysik, kemi och biologi

    Author : Jennie Johansson; [2020]
    Keywords : Acetylation; Epigenetics; Heteroplasmy; Methylation; Mitochondrial haplotype; Mitochondrion; Non coding RNA; Phosphorylation;

    Abstract : This mini-review investigates and compiles the latest knowledge regarding epigenetic changes on the mammalian mitochondrial DNA and its proteins. Methylation of the DNA, acetylation of the proteins and silencing of genes by short non-coding RNAs are the main epigenetic changes known today to affect mitochondrial DNA, mostly leading to repression. READ MORE

  3. 3. Histone modifications and their role in splicing

    University essay from Linköpings universitet/Biologi

    Author : Anna Wettermark; [2020]
    Keywords : Splicing; Spliceosome; Histone modifications; epigenetics; histone methylation; histone acetylation; histone phosphorylation; histone ubiquitination;

    Abstract : Splicing is the process when introns gets removed and exons are spliced together. This is an important step to form a clean mRNA with no unnecessary sequences that could interrupt protein synthesis. There are different types of splicing and some of them need a complex called spliceosome. READ MORE

  4. 4. Studying the effects of Muscone on PANC-1 in vitro

    University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

    Author : Kyriaki Gerontaki; [2020]
    Keywords : ;

    Abstract : In this project cancer was viewed as a metabolic disorder. The study focused on the effect of synthetic muscone on PANC-1 cells. Synthetic muscone is a ketone. Some cancers lack the potential to metabolise ketone bodies, mainly due to mitochondrial dysfunction. READ MORE

  5. 5. Tau phosphorylation on threonine 217 as a potential biomarker for neurodegenerative diseases

    University essay from Högskolan i Borås/Akademin för textil, teknik och ekonomi

    Author : Sukri Omar Jama; [2019]
    Keywords : P217; hyperphosphorylation; Taupathies; CSF; plasma; serum; Simoa; antibodies; assay; Progressive supranuclear palsy; Alzheimer’s disease and Global glial Taupathies; P217; hyperfosforyrlering; Taupathies; CSF; plasma; serum; Simoa; antikroppar; analys; Progressiv supranukleär pares; Corticobasal degeneration och Globular glialtauopati;

    Abstract : Hyperfosforylering av biomarkörproteinet Tau förekommer i flera neurodegenerativa sjukdomar som kallas Taupathies. Proteinets huvudfunktion i människokroppen är att modulera flexibilitet och stabilitet för axonal-mikrotubulin. I Taupathies utlöser hyperfosforyleringen av Tau instabilitet och neurodegenerationen. READ MORE