Essays about: "Cell signalling"

Showing result 6 - 10 of 57 essays containing the words Cell signalling.

  1. 6. GSK-3 and ROS (reactive oxygen species) inhibition modulate Vimentin expression

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ragad Hassano; [2022]
    Keywords : ;

    Abstract : When exposed to pathogenic stress, cellular processes and survival are dependent on cytoskeletal proteins for structure and organisation of the cell to adapt and maintain homeostasis during inflammation. Vimentin is type III cytoskeletal protein, with an extensive cytoplasmic meshwork, across the cell and regulate the cell structure and cellular space and expressed strongly under tumorigenic events. READ MORE

  3. 7. The Effects of ACK1 and Cell Density on ErbB3

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Julia Svensson; [2021]
    Keywords : ;

    Abstract : The ErbB family of receptors are involved in signalling relating to cell proliferation and differentiation through activation of pathways such as PI3K and MAPK. Their overexpression is often found in different cancer types and therefore, their expression is under tight regulation. READ MORE

  4. 8. Validation and optimization of multiplexInSitu PLA for signalling pathway analysis

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Tanay Kumar Sinha; [2021]
    Keywords : Chronic myeloid leukemia Tyrosine kinase inhibitors Proximity ligation assay Cross-reactivity Padlock Template;

    Abstract : With the advent of Tyrosine kinase inhibitors (TKI) as a therapy for Chronic myeloid Leukemia (CML), the patients now enjoy a life expectancy close to that of the general population. But some patients do get unresponsive to the TKI treatment over time due to several mutations in the kinase domain of the BCR-ABL fusion protein, which further leads to activation of multiple signaling cascades within the leukemic cell, helping it survive and proliferate. READ MORE

  5. 9. Fibronectin-mediated interactions of Staphylococcus aureus with human cells

    University essay from Linköpings universitet/Avdelningen för inflammation och infektion

    Author : Joseph Issa; [2021]
    Keywords : Staphylococcus aureus; Fibronectin; FnBP; Integrins; human cells; H1299 cells; Fluorescence microscopy;

    Abstract : Bacteria typically adhere to various cell surfaces present in the human body to colonise or invade human tissues. Staphylococcus aureus (S. aureus) can express the fibronectin-binding proteins A and B (FnBP-A, FnBP-B) that can facilitate the binding of multiple copies of fibronectin (Fn). READ MORE

  6. 10. Development of a reporter gene assay on an automated platform

    University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Author : Fanny Redin; [2021]
    Keywords : Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

    Abstract : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. READ MORE